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Details on Person ATP7A transports cytosolic Cu2+ to phagosomal lumen

Class:Id	Reaction:6803545
_displayName	ATP7A transports cytosolic Cu2+ to phagosomal lumen
_doRelease	TRUE
_timestamp	2016-08-18 11:41:33
authored	[InstanceEdit:6803156] Shamovsky, Veronica, 2015-10-05
catalystActivity	[CatalystActivity:6803542] P-type monovalent copper transporter activity of ATP7A:PDZD11 [phagocytic vesicle membrane]
compartment	[Compartment:70101] cytosol [Compartment:1222282] phagocytic vesicle lumen [Compartment:1222693] phagocytic vesicle membrane
created	[InstanceEdit:6803543] Shamovsky, Veronica, 2015-10-07
edited	[InstanceEdit:8935852] Shamovsky, Veronica, 2016-08-15
input	[SimpleEntity:113592] ATP [cytosol] [SimpleEntity:29356] H2O [cytosol] [Complex:3697875] ATOX1:Cu1+ [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8864786] Copper at the front line of the host-pathogen battle [LiteratureReference:8864765] The Role of Copper and Zinc Toxicity in Innate Immune Defense against Bacterial Pathogens [LiteratureReference:8864787] Copper homeostasis at the host-pathogen interface
modified	[InstanceEdit:8864774] Shamovsky, Veronica, 2016-03-16 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8933034] Shamovsky, Veronica, 2016-08-02 [InstanceEdit:8935889] Shamovsky, Veronica, 2016-08-15 [InstanceEdit:8936377] Shamovsky, Veronica, 2016-08-18 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ATP7A transports cytosolic Cu2+ to phagosomal lumen Copper export from cells by copper-transporting ATPase1
output	[SimpleEntity:29372] Pi [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:6803540] Cu1+ [phagocytic vesicle lumen] [EntityWithAccessionedSequence:3697884] ATOX1 [cytosol] [Homo sapiens]
releaseDate	2016-09-19
reviewed	[InstanceEdit:8933035] Hains, David S, 2016-08-02 [InstanceEdit:8867536] Jupe, Steve, 2016-04-15
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8883007] R-HSA-6803545.2
summation	[Summation:8864801] Copper is an essential cofactor of key metabolic enzymes (Li...
(hasEvent)	[Pathway:6803544] Ion influx/efflux at host-pathogen interface [Homo sapiens]
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No pathways have been reviewed or authored by ATP7A transports cytosolic Cu2+ to phagosomal lumen (6803545)