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Details on Person TP53 stimulates PCBP4 expression

Class:Id	BlackBoxEvent:6803400
_displayName	TP53 stimulates PCBP4 expression
_doRelease	TRUE
_timestamp	2016-02-19 18:22:48
authored	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:6803398] Orlic-Milacic, Marija, 2015-10-06
edited	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
input	[EntityWithAccessionedSequence:6803390] PCBP4 Gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:6803393] MCG10, a novel p53 target gene that encodes a KH domain RNA-binding protein, is capable of inducing apoptosis and cell cycle arrest in G(2)-M
modified	[InstanceEdit:6809228] Orlic-Milacic, Marija, 2015-11-09 [InstanceEdit:6809229] Orlic-Milacic, Marija, 2015-11-09 [InstanceEdit:6809236] Orlic-Milacic, Marija, 2015-11-09 [InstanceEdit:6810438] Orlic-Milacic, Marija, 2015-11-17 [InstanceEdit:8856095] Orlic-Milacic, Marija, 2016-02-08 [InstanceEdit:8856587] Orlic-Milacic, Marija, 2016-02-10 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TP53 stimulates PCBP4 expression
output	[EntityWithAccessionedSequence:6803382] PCBP4 [cytosol] [Homo sapiens]
precedingEvent	[Reaction:6803391] TP53 binds the PCBP4 gene [Homo sapiens] [Reaction:6799246] CHEK1 phosphorylates TP53 [Homo sapiens] [Reaction:69685] CHEK2 phosphorylates TP53 [Homo sapiens] [Reaction:6805285] PLK3 phosphorylates TP53 [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:6803401] Positive gene expression regulation by 'p-S15,S20-TP53 Tetramer:PCBP4 Gene [nucleoplasm]'
regulationReference	[RegulationReference:9641562] Positive gene expression regulation by 'p-S15,S20-TP53 Tetramer:PCBP4 Gene [nucleoplasm]' MCG10, a novel p53 target gene that encodes a KH domain RNA-binding protein, is capable of inducing apoptosis and cell cycle arrest in G(2)-M
releaseDate	2016-03-23
releaseStatus	NEW
reviewed	[InstanceEdit:8855677] Zaccara, Sara, 2016-02-04 [InstanceEdit:8855680] Inga, Alberto, 2016-02-04
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8861436] R-HSA-6803400.4
summation	[Summation:6803399] Binding of TP53 (p53) to two p53 response elements in the pr...
(hasEvent)	[Pathway:6804116] TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest [Homo sapiens]
(precedingEvent)	[Reaction:6803403] PCBP4 binds the CDKN1A mRNA [Homo sapiens]
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No pathways have been reviewed or authored by TP53 stimulates PCBP4 expression (6803400)