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Details on Person gain_of_function of high kinase activity BRAF mutants [cytosol]
| Class:Id | EntityFunctionalStatus:6802883 |
|---|---|
| _displayName | gain_of_function of high kinase activity BRAF mutants [cytosol] |
| _timestamp | 2015-10-02 19:11:51 |
| created | [InstanceEdit:6802882] Rothfels, Karen, 2015-10-02 |
| diseaseEntity | [DefinedSet:6802579] high kinase activity BRAF mutants [cytosol] [Homo sapiens] |
| functionalStatus | [FunctionalStatus:2362351] gain_of_function via non_conservative_missense_variant [FunctionalStatus:5637717] gain_of_function via inframe_insertion |
| modified | [InstanceEdit:9631717] Wu, G, 2018-12-12 |
| normalEntity | [Complex:5672718] p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] [Homo sapiens] |
| (entityFunctionalStatus) | [Reaction:6802912] High kinase activity BRAF mutants bind MAP2Ks and MAPKs [Homo sapiens] [Reaction:6802938] Inhibitors bind and inhibit highly active BRAF mutants [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by gain_of_function of high kinase activity BRAF mutants [cytosol] (6802883)
