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Details on Person p-BRAF/RAF fusion dimers:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [cytosol]

Class:Id	Complex:6802711
_displayName	p-BRAF/RAF fusion dimers:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [cytosol]
_timestamp	2016-07-15 23:49:31
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:6802712] Rothfels, Karen, 2015-10-02
disease	[Disease:1500689] cancer
hasComponent	[CandidateSet:6802698] p-BRAF/RAF fusion dimers [cytosol] [Homo sapiens] [CandidateSet:5672717] RAF/MAPK scaffolds [cytosol] [Homo sapiens] [DefinedSet:5672721] p-2S MAP2K homo/heterodimers [cytosol] [Homo sapiens] [DefinedSet:169289] p-T,Y MAPKs [cytosol] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15
name	p-BRAF/RAF fusion dimers:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8897291] R-HSA-6802711.1
(diseaseEntity)	[EntityFunctionalStatus:6802904] gain_of_function of p-BRAF/RAF fusion dimers:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [cytosol]
(input)	[Reaction:6802932] Dissociation of BRAF/RAF fusion complex [Homo sapiens]
(output)	[Reaction:6802935] MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9896530] Update Tracker - [Complex:6802711] p-BRAF/RAF fusion dimers:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [cytosol] - v60:[updateContainedComponent] [_UpdateTracker:9898026] Update Tracker - [Complex:6802711] p-BRAF/RAF fusion dimers:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [cytosol] - v63:[updateContainedComponent] [_UpdateTracker:9898838] Update Tracker - [Complex:6802711] p-BRAF/RAF fusion dimers:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [cytosol] - v64:[updateContainedComponent] [_UpdateTracker:9899864] Update Tracker - [Complex:6802711] p-BRAF/RAF fusion dimers:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [cytosol] - v67:[updateContainedComponent] [_UpdateTracker:9919869] Update Tracker - [Complex:6802711] p-BRAF/RAF fusion dimers:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [cytosol] - v90:[updateContainedComponent] [_UpdateTracker:9928555] Update Tracker - [Complex:6802711] p-BRAF/RAF fusion dimers:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [cytosol] - v91:[updateContainedComponent]
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No pathways have been reviewed or authored by p-BRAF/RAF fusion dimers:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [cytosol] (6802711)