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Details on Person RAS mutants:GTP [plasma membrane]

Class:Id	Complex:6802607
_displayName	RAS mutants:GTP [plasma membrane]
_timestamp	2019-06-18 19:04:42
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:6802606] Rothfels, Karen, 2015-10-02
disease	[Disease:1500689] cancer
hasComponent	[SimpleEntity:29438] GTP [cytosol] [DefinedSet:9649713] RAS mutants [plasma membrane] [Homo sapiens]
includedLocation	[Compartment:70101] cytosol
isChimeric	FALSE
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9649766] Rothfels, Karen, 2019-06-14 [InstanceEdit:9649907] Rothfels, Karen, 2019-06-18
name	RAS mutants:GTP
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8929415] R-HSA-6802607.2
(diseaseEntity)	[EntityFunctionalStatus:6802836] loss_of_function of RAS mutants:GTP [plasma membrane] [EntityFunctionalStatus:6802863] gain_of_function of RAS mutants:GTP [plasma membrane]
(hasComponent)	[Complex:6802611] RAS mutants:GTP:RAF homo/heterodimer [plasma membrane] [Homo sapiens] [Complex:6802617] RAS mutants:GTP:p-RAF homo/heterodimer [plasma membrane] [Homo sapiens] [Complex:6802633] mutant RAS:inactive BRAF:p-S338,T491,S494,S729 RAF1 [plasma membrane] [Homo sapiens] [Complex:6802674] mutant RAS:inactive BRAF:RAF1 [plasma membrane] [Homo sapiens] [Complex:6803238] RAS mutants:GTP:RAF [plasma membrane] [Homo sapiens] [Complex:8936725] chemically or genetically inactive BRAF mutants:mutant RAS:GTP [plasma membrane] [Homo sapiens]
(input)	[Reaction:6802908] RAS mutants bind inactive RAF [Homo sapiens] [Reaction:6802937] Inactive BRAF mutants bind mutant RAS:GTP [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9900849] Update Tracker - [Complex:6802607] RAS mutants:GTP [plasma membrane] - v70:[add_removeHasComponent]
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No pathways have been reviewed or authored by RAS mutants:GTP [plasma membrane] (6802607)