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Details on Person FAM131B(1-18)-p-BRAF(381-766) fusion [cytosol]

Class:Id	EntityWithAccessionedSequence:6802527
_displayName	FAM131B(1-18)-p-BRAF(381-766) fusion [cytosol]
_timestamp	2021-09-13 19:33:45
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:6802528] Rothfels, Karen, 2015-10-02
disease	[Disease:6802279] pilocytic astrocytoma
endCoordinate	18
hasModifiedResidue	[FragmentInsertionModification:6802322] Insertion of residues 381 to 766 at 19 from UniProt:P15056 BRAF [ModifiedResidue:5672668] O-phospho-L-serine at 446 [ModifiedResidue:5672670] O-phospho-L-serine at 729 [ModifiedResidue:5672675] O-phospho-L-threonine at 599 [ModifiedResidue:5672677] O-phospho-L-serine at 602
literatureReference	[LiteratureReference:6800633] Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9753817] Rothfels, Karen, 2021-09-13
name	FAM131B(1-18)-p-BRAF(381-766) fusion
referenceEntity	[ReferenceGeneProduct:228802] UniProt:Q86XD5 FAM131B [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8891742] R-HSA-6802527.2
startCoordinate	1
(hasComponent)	[Complex:6802700] p-FAM131B-BRAF fusion dimer [cytosol] [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9902916] Update Tracker - [EntityWithAccessionedSequence:6802527] FAM131B(1-18)-p-BRAF(381-766) fusion [cytosol] - v79:[modifyName]
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No pathways have been reviewed or authored by FAM131B(1-18)-p-BRAF(381-766) fusion [cytosol] (6802527)