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Details on Person SND1(1-593)-BRAF(381-766) fusion [cytosol]

Class:Id	EntityWithAccessionedSequence:6802469
_displayName	SND1(1-593)-BRAF(381-766) fusion [cytosol]
_timestamp	2021-09-13 19:05:32
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:6802470] Rothfels, Karen, 2015-10-02
disease	[Disease:1500689] cancer [Disease:6802264] gastric adenocarcinoma
endCoordinate	593
hasModifiedResidue	[FragmentInsertionModification:6802468] Insertion of residues 381 to 766 at 594 from UniProt:P15056 BRAF [ModifiedResidue:5672668] O-phospho-L-serine at 446 [ModifiedResidue:5672670] O-phospho-L-serine at 729
literatureReference	[LiteratureReference:6800629] A novel SND1-BRAF fusion confers resistance to c-Met inhibitor PF-04217903 in GTL16 cells through [corrected] MAPK activation
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9753816] Rothfels, Karen, 2021-09-13
name	SND1(1-593)-BRAF(381-766) fusion
referenceEntity	[ReferenceGeneProduct:248735] UniProt:Q7KZF4 SND1 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8921800] R-HSA-6802469.2
startCoordinate	1
(hasComponent)	[Complex:6802650] SND1-BRAF fusion dimer [cytosol] [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9902894] Update Tracker - [EntityWithAccessionedSequence:6802469] SND1(1-593)-BRAF(381-766) fusion [cytosol] - v79:[modifyName]
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No pathways have been reviewed or authored by SND1(1-593)-BRAF(381-766) fusion [cytosol] (6802469)