Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
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Details on Person The class I ATP competitive inhibitors vemurafenib and dabra...
| Class:Id | Summation:6802240 |
|---|---|
| _displayName | The class I ATP competitive inhibitors vemurafenib and dabra... |
| _timestamp | 2015-10-02 18:52:22 |
| created | [InstanceEdit:6802239] Rothfels, Karen, 2015-10-02 |
| text | The class I ATP competitive inhibitors vemurafenib and dabrafenib have been approved for treatment of V600E melanoma, and other BRAF-selective inhibitors are in clinical and preclinical trials. These inhibitors bind to the active conformation of the enzyme promoted by the V600E mutation (King et al, 2006; Tsai et al, 2008). |
| (summation) | [Reaction:6802938] Inhibitors bind and inhibit highly active BRAF mutants [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by The class I ATP competitive inhibitors vemurafenib and dabra... (6802240)
