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Details on Person TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane

Class:Id	Reaction:6801250
_displayName	TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane
_doRelease	TRUE
_timestamp	2017-02-23 15:44:14
authored	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
catalystActivity	[CatalystActivity:6801253] lipid transporter activity of TRIAP1:PRELID1, PRELID3A [mitochondrial intermembrane space]
compartment	[Compartment:17906] mitochondrial outer membrane [Compartment:70616] mitochondrial inner membrane [Compartment:17927] mitochondrial intermembrane space
created	[InstanceEdit:6801252] Orlic-Milacic, Marija, 2015-10-01
edited	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
input	[SimpleEntity:1500590] PA [mitochondrial outer membrane]
isChimeric	FALSE
literatureReference	[LiteratureReference:6801241] TRIAP1/PRELI complexes prevent apoptosis by mediating intramitochondrial transport of phosphatidic acid [LiteratureReference:8870824] Structural insight into the TRIAP1/PRELI-like domain family of mitochondrial phospholipid transfer complexes
modified	[InstanceEdit:6809228] Orlic-Milacic, Marija, 2015-11-09 [InstanceEdit:6809229] Orlic-Milacic, Marija, 2015-11-09 [InstanceEdit:6809233] Orlic-Milacic, Marija, 2015-11-09 [InstanceEdit:6810435] Orlic-Milacic, Marija, 2015-11-16 [InstanceEdit:6810437] Orlic-Milacic, Marija, 2015-11-17 [InstanceEdit:8856076] Orlic-Milacic, Marija, 2016-02-08 [InstanceEdit:8856587] Orlic-Milacic, Marija, 2016-02-10 [InstanceEdit:8870820] Jassal, Bijay, 2016-05-12 [InstanceEdit:8933572] Jassal, Bijay, 2016-08-08 [InstanceEdit:8979248] Orlic-Milacic, Marija, 2017-02-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane
output	[SimpleEntity:1524101] PA [mitochondrial inner membrane]
precedingEvent	[Reaction:1482548] 1-acyl LPA is acylated to PA by AGPAT5 (OM) [Homo sapiens] [Reaction:1482695] G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) [Homo sapiens] [Reaction:1482604] PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) [Homo sapiens] [Reaction:6801242] TRIAP1 binds PRELID1, PRELID3A [Homo sapiens] [BlackBoxEvent:6801213] TP53 stimulates TRIAP1 expression [Homo sapiens]
releaseDate	2016-03-23
releaseStatus	NEW
reviewed	[InstanceEdit:8855677] Zaccara, Sara, 2016-02-04 [InstanceEdit:8855680] Inga, Alberto, 2016-02-04
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8861109] R-HSA-6801250.5
summation	[Summation:6801251] The complex of TP53-regulated inhibitor of apoptosis 1 (TRIA...
(hasEvent)	[Pathway:6803204] TP53 Regulates Transcription of Genes Involved in Cytochrome C Release [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9783197] Update Tracker - [Reaction:6801250] TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane - v57:[addLiteratureReference, modifyText]
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