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Details on Person Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas

Class:IdLiteratureReference:6800638
_displayNameTandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas
_timestamp2015-09-29 16:50:06
author[Person:6800547] Jones, David T W
[Person:6800553] Kocialkowski, Sylvia
[Person:6800568] Liu, Lu
[Person:6800587] Pearson, Danita M
[Person:6800508] Bäcklund, L Magnus
[Person:6800538] Ichimura, Koichi
[Person:6800520] Collins, V Peter
created[InstanceEdit:6800637] Rothfels, Karen, 2015-09-29
journalCancer Res.
pages8673-7
pubMedIdentifier18974108
titleTandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas
volume68
year2008
(literatureReference)[Reaction:6802927] BRAF and RAF fusion mutant dimers are phosphorylated [Homo sapiens]
[Reaction:6802932] Dissociation of BRAF/RAF fusion complex [Homo sapiens]
[Reaction:6802933] p-BRAF and RAF fusion dimers phosphorylate MAP2Ks [Homo sapiens]
[Reaction:6802934] p-BRAF and RAF fusion dimers bind MAP2Ks and MAPKs [Homo sapiens]
[Reaction:6802935] MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers [Homo sapiens]
[Pathway:6802952] Signaling by BRAF and RAF1 fusions [Homo sapiens]
[EntityWithAccessionedSequence:6802393] KIAA1549(1-1749)-BRAF(381-766) fusion [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:6802534] KIAA1549(1-1749)-p-BRAF(381-766) fusion [plasma membrane] [Homo sapiens]
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