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Details on Person Binding of TP53 (p53) to p53 response elements in the first ...
| Class:Id | Summation:6800027 |
|---|---|
| _displayName | Binding of TP53 (p53) to p53 response elements in the first ... |
| _timestamp | 2016-02-08 17:33:54 |
| created | [InstanceEdit:6800019] Orlic-Milacic, Marija, 2015-09-26 |
| modified | [InstanceEdit:6803275] Orlic-Milacic, Marija, 2015-10-05 [InstanceEdit:8856049] Orlic-Milacic, Marija, 2016-02-08 |
| text | Binding of TP53 (p53) to p53 response elements in the first and second introns of the IGFBP3 gene upregulates IGFBP3 transcription (Buckbinder et al. 1995). IGFBP3 is one of a family of six homologous proteins that bind IGF1 and IGF2 with high affinity. IGFBP3 contributes to cellular apoptosis in both IGF-dependent and IGF-independent manner (Marzec et al. 2015). |
| (summation) | [BlackBoxEvent:6800044] TP53 stimulates IGFBP3 expression [Homo sapiens] |
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No pathways have been reviewed or authored by Binding of TP53 (p53) to p53 response elements in the first ... (6800027)
