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Details on Person TP53 family members bind PPP1R13B or TP53BP2

Class:IdReaction:6799777
_displayNameTP53 family members bind PPP1R13B or TP53BP2
_doReleaseTRUE
_timestamp2017-02-23 17:27:37
authored[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:6799774] Orlic-Milacic, Marija, 2015-09-25
edited[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
input[DefinedSet:6798076] p-S15,S20-TP53,TP63,TP73 [nucleoplasm] [Homo sapiens]
[DefinedSet:6799786] PPP1R13B,TP53BP2 [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:6799790] Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax
[LiteratureReference:6799748] Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73
[LiteratureReference:6799772] ASPP proteins specifically stimulate the apoptotic function of p53
[LiteratureReference:6799791] ASPP1 and ASPP2: common activators of p53 family members
modified[InstanceEdit:8856568] Orlic-Milacic, Marija, 2016-02-10
[InstanceEdit:8856587] Orlic-Milacic, Marija, 2016-02-10
[InstanceEdit:8856588] Orlic-Milacic, Marija, 2016-02-10
[InstanceEdit:8979262] Orlic-Milacic, Marija, 2017-02-23
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameTP53 family members bind PPP1R13B or TP53BP2
p53 family members bind ASPP1 or ASPP2
output[Complex:6799788] (p-S15,S20-TP53,TP63,TP73):(PPP1R13B,TP53BP2) [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2016-03-23
releaseStatusNEW
reviewed[InstanceEdit:8855677] Zaccara, Sara, 2016-02-04
[InstanceEdit:8855680] Inga, Alberto, 2016-02-04
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8861118] R-HSA-6799777.3
summation[Summation:6799781] TP53 (p53) forms a complex with PPP1R13B (ASPP1) or TP53BP2 ...
(hasEvent)[Pathway:6804759] Regulation of TP53 Activity through Association with Co-factors [Homo sapiens]
(precedingEvent)[Reaction:3700981] TP53 family members bind the BAX promoter [Homo sapiens]
[Reaction:4331340] TP53 binds the BBC3 (PUMA) promoter [Homo sapiens]
[Reaction:6799462] TP53 family members bind the TP53I3 (PIG3) gene promoter [Homo sapiens]
[Reaction:6799815] TP53 family members bind the FAS gene [Homo sapiens]
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No pathways have been reviewed or authored by TP53 family members bind PPP1R13B or TP53BP2 (6799777)
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