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Details on Person MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5

Class:IdReaction:6799545
_displayNameMAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5
_doReleaseTRUE
_timestamp2016-02-19 18:20:42
authored[InstanceEdit:6799498] Jassal, Bijay, 2015-09-25
catalystActivity[CatalystActivity:6799539] alpha-mannosidase activity of MAN2C1:Zn2+ [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:6799541] Jassal, Bijay, 2015-09-25
edited[InstanceEdit:6799498] Jassal, Bijay, 2015-09-25
input[SimpleEntity:6799540] alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc [cytosol]
[SimpleEntity:29356] H2O [cytosol]
[SimpleEntity:29356] H2O [cytosol]
[SimpleEntity:29356] H2O [cytosol]
[SimpleEntity:29356] H2O [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:6799550] Man2C1, an alpha-mannosidase, is involved in the trimming of free oligosaccharides in the cytosol
modified[InstanceEdit:6799596] Jassal, Bijay, 2015-09-25
[InstanceEdit:8851786] Jassal, Bijay, 2016-01-11
[InstanceEdit:8853373] Jassal, Bijay, 2016-01-22
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameMAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5
output[SimpleEntity:6799543] alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc [cytosol]
[SimpleEntity:429579] Man [cytosol]
[SimpleEntity:429579] Man [cytosol]
[SimpleEntity:429579] Man [cytosol]
[SimpleEntity:429579] Man [cytosol]
releaseDate2016-03-23
releaseStatusNEW
reviewed[InstanceEdit:8851787] D'Eustachio, Peter, 2016-01-11
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8861124] R-HSA-6799545.2
summation[Summation:6799549] Endoplasmic reticulum-associated degradation of misfolded gl...
(hasEvent)[Pathway:8853383] Lysosomal oligosaccharide catabolism [Homo sapiens]
(precedingEvent)[BlackBoxEvent:8853391] GlcNAc (Man)5 translocates from cytosol to lysosomal lumen [Homo sapiens]
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No pathways have been reviewed or authored by MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 (6799545)