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Details on Person GLYCTK phosphorylates DGA to 3PDGA

Class:Id	Reaction:6799495
_displayName	GLYCTK phosphorylates DGA to 3PDGA
_doRelease	TRUE
_timestamp	2023-05-30 20:57:11
authored	[InstanceEdit:6799498] Jassal, Bijay, 2015-09-25
catalystActivity	[CatalystActivity:6799496] glycerate kinase activity of GLYCTK [cytosol]
catalystActivityReference	[CatalystActivityReference:9835578] glycerate kinase activity of GLYCTK [cytosol] D-glycerate kinase deficiency as a cause of D-glyceric aciduria
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:6799498] Jassal, Bijay, 2015-09-25
edited	[InstanceEdit:6799498] Jassal, Bijay, 2015-09-25
input	[SimpleEntity:6799497] DGA [cytosol] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:6799501] Isolation and characterization of the human D-glyceric acidemia related glycerate kinase gene GLYCTK1 and its alternatively splicing variant GLYCTK2 [LiteratureReference:6799503] D-glycerate kinase deficiency as a cause of D-glyceric aciduria [LiteratureReference:6799482] D-glyceric aciduria is caused by genetic deficiency of D-glycerate kinase (GLYCTK)
modified	[InstanceEdit:6799596] Jassal, Bijay, 2015-09-25 [InstanceEdit:6813751] Jassal, Bijay, 2015-11-24 [InstanceEdit:6813752] Jassal, Bijay, 2015-11-24 [InstanceEdit:8851786] Jassal, Bijay, 2016-01-11 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9832974] D'Eustachio, Peter, 2023-04-11 [InstanceEdit:9835574] D'Eustachio, Peter, 2023-05-16 [InstanceEdit:9835577] D'Eustachio, Peter, 2023-05-16 [InstanceEdit:9836604] D'Eustachio, Peter, 2023-05-30
name	GLYCTK phosphorylates DGA to 3PDGA (R)-glycerate + ATP => (2R)-3-phosphoglycerate + ADP + H(+)
output	[SimpleEntity:6799493] 3PDGA [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:70106] H+ [cytosol]
precedingEvent	[Reaction:6813749] ALDH1A1 oxidises GA to DGA [Homo sapiens] [Reaction:70342] ALDOB tetramer cleaves Fru-1-P to GA and DHAP [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821384] two stars
releaseDate	2016-03-23
releaseStatus	NEW
reviewed	[InstanceEdit:8851787] D'Eustachio, Peter, 2016-01-11 [InstanceEdit:9835575] Hill, David P, 2023-05-16
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8861123] R-HSA-6799495.3
structureModified	[InstanceEdit:9832974] D'Eustachio, Peter, 2023-04-11
summation	[Summation:6799492] D-glyceric acid (DGA) is an intermediate of serine catabolis...
(hasEvent)	[Pathway:70350] Fructose catabolism [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9835785] Update Tracker - [Reaction:6799495] GLYCTK phosphorylates DGA to 3PDGA - v85:[modifyText]
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