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Details on Person TP53 stimulates expression of the TP53I3 (PIG3) gene

Class:Id	BlackBoxEvent:6799441
_displayName	TP53 stimulates expression of the TP53I3 (PIG3) gene
_doRelease	TRUE
_timestamp	2016-02-19 18:22:45
authored	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6799451] Orlic-Milacic, Marija, 2015-09-24
edited	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
input	[EntityWithAccessionedSequence:6799446] TP53I3 Gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:6799447] A polymorphic microsatellite that mediates induction of PIG3 by p53 [LiteratureReference:6799772] ASPP proteins specifically stimulate the apoptotic function of p53 [LiteratureReference:6799791] ASPP1 and ASPP2: common activators of p53 family members
modified	[InstanceEdit:6799468] Orlic-Milacic, Marija, 2015-09-25 [InstanceEdit:6799799] Orlic-Milacic, Marija, 2015-09-25 [InstanceEdit:6803273] Orlic-Milacic, Marija, 2015-10-05 [InstanceEdit:6809228] Orlic-Milacic, Marija, 2015-11-09 [InstanceEdit:6809229] Orlic-Milacic, Marija, 2015-11-09 [InstanceEdit:6809233] Orlic-Milacic, Marija, 2015-11-09 [InstanceEdit:6810435] Orlic-Milacic, Marija, 2015-11-16 [InstanceEdit:6810437] Orlic-Milacic, Marija, 2015-11-17 [InstanceEdit:8856083] Orlic-Milacic, Marija, 2016-02-08 [InstanceEdit:8856587] Orlic-Milacic, Marija, 2016-02-10 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TP53 stimulates expression of the TP53I3 (PIG3) gene
output	[EntityWithAccessionedSequence:6799460] TP53I3 [cytosol] [Homo sapiens]
precedingEvent	[Reaction:6799462] TP53 family members bind the TP53I3 (PIG3) gene promoter [Homo sapiens] [Reaction:6799777] TP53 family members bind PPP1R13B or TP53BP2 [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:6799452] Positive gene expression regulation by '(p-S15,S20-TP53,TP63,TP73):(PPP1R13B,TP53BP2):TP53I3 Gene [nucleoplasm]'
regulationReference	[RegulationReference:9642884] Positive gene expression regulation by '(p-S15,S20-TP53,TP63,TP73):(PPP1R13B,TP53BP2):TP53I3 Gene [nucleoplasm]' A polymorphic microsatellite that mediates induction of PIG3 by p53
releaseDate	2016-03-23
releaseStatus	NEW
reviewed	[InstanceEdit:8855677] Zaccara, Sara, 2016-02-04 [InstanceEdit:8855680] Inga, Alberto, 2016-02-04
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8861429] R-HSA-6799441.4
summation	[Summation:6799459] TP53 (p53) activates transcription of the TP53I3 (PIG3) gene...
(hasEvent)	[Pathway:6803205] TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain [Homo sapiens]
(precedingEvent)	[Reaction:6799466] TP53I3 dimerizes [Homo sapiens]
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No pathways have been reviewed or authored by TP53 stimulates expression of the TP53I3 (PIG3) gene (6799441)