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Details on Person RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)
| Class:Id | LiteratureReference:6799060 |
| _displayName | RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E) |
| _timestamp | 2015-09-21 15:56:17 |
| author | [Person:6790389] Poulikakos, Poulikos I [Person:6798969] Persaud, Yogindra [Person:6798892] Janakiraman, Manickam [Person:6798908] Kong, Xiangju [Person:6798957] Ng, Charles [Person:6798946] Moriceau, Gatien [Person:6798995] Shi, Hubing [Person:6798819] Atefi, Mohammad [Person:6799019] Titz, Bjoern [Person:6798865] Gabay, May Tal [Person:6798981] Salton, Maayan [Person:6798840] Dahlman, Kimberly B [Person:6799010] Tadi, Madhavi [Person:6799030] Wargo, Jennifer A [Person:6798860] Flaherty, Keith T [Person:6798903] Kelley, Mark C [Person:5687896] Misteli, Tom [Person:6798826] Chapman, Paul B [Person:6799003] Sosman, Jeffrey A [Person:6798872] Graeber, Thomas G [Person:6798974] Ribas, Antoni [Person:6798932] Lo, Roger S [Person:1218832] Rosen, N [Person:6790436] Solit, David B |
| created | [InstanceEdit:6799061] Rothfels, Karen, 2015-09-21 |
| journal | Nature |
| pages | 387-90 |
| pubMedIdentifier | 22113612 |
| title | RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E) |
| volume | 480 |
| year | 2011 |
| (literatureReference) | [EntityWithAccessionedSequence:6802486] BRAF V600E;V169_D380del [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:6802489] BRAF V600E;V169_M438del [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:6802491] BRAF V600E;V47_D380del [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:6802495] BRAF V600E;V47_M438del [cytosol] [Homo sapiens] [DefinedSet:6802657] V600E BRAF splice variants [cytosol] [Homo sapiens] [Reaction:6802930] Dimerization of BRAF V600E splice variants contributes to BRAF inhibitor resistance [Homo sapiens] [Pathway:6802948] Signaling by high-kinase activity BRAF mutants [Homo sapiens] |
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No pathways have been reviewed or authored by RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E) (6799060)