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Details on Person S100A8:S100A9 binds Mn2+

Class:IdReaction:6798528
_displayNameS100A8:S100A9 binds Mn2+
_doReleaseTRUE
_timestamp2016-11-03 16:16:17
authored[InstanceEdit:6803156] Shamovsky, Veronica, 2015-10-05
compartment[Compartment:984] extracellular region
created[InstanceEdit:6798553] Shamovsky, Veronica, 2015-09-19
edited[InstanceEdit:8935852] Shamovsky, Veronica, 2016-08-15
input[SimpleEntity:266099] Mn2+ [extracellular region]
[SimpleEntity:74113] Na+ [extracellular region]
[SimpleEntity:74113] Na+ [extracellular region]
[SimpleEntity:266099] Mn2+ [extracellular region]
[Complex:8944198] S100A8:S100A9:Ca2+ [extracellular region] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:6798486] Manganese binding properties of human calprotectin under conditions of high and low calcium: X-ray crystallographic and advanced electron paramagnetic resonance spectroscopic analysis
[LiteratureReference:6798544] Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens
[LiteratureReference:6798470] High-affinity manganese coordination by human calprotectin is calcium-dependent and requires the histidine-rich site formed at the dimer interface
modified[InstanceEdit:8879167] Shamovsky, Veronica, 2016-07-15
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:8933100] Shamovsky, Veronica, 2016-08-02
[InstanceEdit:8935892] Shamovsky, Veronica, 2016-08-15
[InstanceEdit:8936377] Shamovsky, Veronica, 2016-08-18
[InstanceEdit:8944199] Shamovsky, Veronica, 2016-11-03
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameS100A8:S100A9 binds Mn2+
output[Complex:6798411] S100A8:S100A9:Ca2+:Mn2+:Na+ [extracellular region] [Homo sapiens]
releaseDate2016-09-19
reviewed[InstanceEdit:8933035] Hains, David S, 2016-08-02
[InstanceEdit:8867536] Jupe, Steve, 2016-04-15
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8922044] R-HSA-6798528.3
summation[Summation:6798406] S100A8 and S100A9 are calcium-binding regulators of inflamma...
(hasEvent)[Pathway:6799990] Metal sequestration by antimicrobial proteins [Homo sapiens]
(updatedInstance)[_UpdateTracker:9782598] Update Tracker - [Reaction:6798528] S100A8:S100A9 binds Mn2+ - v59:[add_removeInput]
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No pathways have been reviewed or authored by S100A8:S100A9 binds Mn2+ (6798528)