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Details on Person p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes

Class:IdLiteratureReference:6798264
_displayNamep53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes
_timestamp2018-07-10 18:33:05
author[Person:6798288] Benson, E K
[Person:6798279] Mungamuri, S K
[Person:6798267] Attie, O
[Person:6798271] Kracikova, M
[Person:6798278] Sachidanandam, R
[Person:6798281] Manfredi, James J
[Person:3769057] Aaronson, Stuart A
created[InstanceEdit:6798277] Orlic-Milacic, Marija, 2015-09-17
journalOncogene
modified[InstanceEdit:9033389] D'Eustachio, Peter, 2017-12-20
[InstanceEdit:9613059] D'Eustachio, Peter, 2018-07-10
pages3959-69
pubMedIdentifier24096481
titlep53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes
volume33
year2014
(literatureReference)[Complex:6798290] p-S15,S20-TP53 Tetramer:E2F4:(TFDP1,TFDP2):(RBL1,RBL2):CDC25C Gene [nucleoplasm] [Homo sapiens]
[RegulationReference:9642489] Negative gene expression regulation by 'p-S15,S20-TP53 Tetramer:E2F4:(TFDP1,TFDP2):(RBL1,RBL2):CDC25C Gene [nucleoplasm]' DNA damage-induced downregulation of Cdc25C is mediated by p53 via two independent mechanisms: one involves direct binding to the cdc25C promoter
[Pathway:6791312] TP53 Regulates Transcription of Cell Cycle Genes [Homo sapiens]
[BlackBoxEvent:6798268] TP53 and E2F4 inhibit CDC25C expression [Homo sapiens]
[Reaction:6798282] TP53 and E2F4 bind the CDC25C gene [Homo sapiens]
[Pathway:6804114] TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest [Homo sapiens]
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