Query author contributions in Reactome
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Details on Person Human plasticity-related genes (PRGs, lipid phosphate phosph...
| Class:Id | Summation:6797644 |
|---|---|
| _displayName | Human plasticity-related genes (PRGs, lipid phosphate phosph... |
| _timestamp | 2015-09-15 13:39:34 |
| created | [InstanceEdit:6797639] Jassal, Bijay, 2015-09-15 |
| text | Human plasticity-related genes (PRGs, lipid phosphate phosphatase-related proteins LPPRs) comprise 5 members expressed in the CNS. They are membrane-spanning enzymes thought to mediate the extracellular concentration and signal transduction of lipid phosphate esters such as lysophosphatidic acid (LPA) and spingosine-1 phosphate (S1P) by hydrolysing their phosphate groups. LPPR4 has been shown to act as an ecto-enzyme in axon growth and regenerative sprouting by mediating LPA levels (Brauer et al. 2003). The activity of the other LPPR members has yet to be defined (Strauss & Brauer 2013). |
| (summation) | [Reaction:6797630] LRPP4(LRPP1-3,5) hydrolyse LPA [Homo sapiens] |
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No pathways have been reviewed or authored by Human plasticity-related genes (PRGs, lipid phosphate phosph... (6797644)
