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Details on Person Shamovsky, Veronica, 2015-08-25
| Class:Id | InstanceEdit:6792550 |
| _displayName | Shamovsky, Veronica, 2015-08-25 |
| _timestamp | 2015-08-25 07:49:33 |
| author | [Person:429259] Shamovsky, Veronica |
| dateTime | 2015-08-25 11:49:26 |
| (edited) | [Reaction:5684248] SCF betaTrCP1,2 binds p-NFkB p105:TPL2:ABIN2 [Homo sapiens] [Reaction:5684250] SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 [Homo sapiens] [Reaction:5684261] MAP3K8 is phosphorylated [Homo sapiens] [Pathway:5684264] MAP3K8 (TPL2)-dependent MAPK1/3 activation [Homo sapiens] [Reaction:5684267] IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex [Homo sapiens] [BlackBoxEvent:5684273] 3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 [Homo sapiens] [Reaction:5684275] IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 [Homo sapiens] |
| (modified) | [Pathway:450294] MAP kinase activation [Homo sapiens] [Reaction:451634] NFKB p105, TPL2 (COT) and ABIN2 form a stable complex [Homo sapiens] [Reaction:5684248] SCF betaTrCP1,2 binds p-NFkB p105:TPL2:ABIN2 [Homo sapiens] [Reaction:5684250] SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2 [Homo sapiens] [Reaction:5684261] MAP3K8 is phosphorylated [Homo sapiens] [Pathway:5684264] MAP3K8 (TPL2)-dependent MAPK1/3 activation [Homo sapiens] [Reaction:5684267] IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex [Homo sapiens] [BlackBoxEvent:5684273] 3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 [Homo sapiens] [Reaction:5684275] IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 [Homo sapiens] |
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No pathways have been reviewed or authored by Shamovsky, Veronica, 2015-08-25 (6792550)