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Details on Person UniProt:C7IVR4-4 pqn-41

Class:IdReferenceIsoform:6791599
_chainChangeLogchain:1-2049 added on Fri August 21 2015
_displayNameUniProt:C7IVR4-4 pqn-41
_timestamp2023-11-03 17:33:08
chainchain:1-2049
checksum4D065563C1BCA233
commentFUNCTION In males, required for non-apoptotic death of the linker cell once it has finished guiding gonad elongation at the end of larval development. May be involved in nuclear envelope crenellation in the linker cell.FUNCTION In males, promotes linker cell survival.FUNCTION In males, promotes linker cell survival.SUBCELLULAR LOCATION Forms aggregates.SUBCELLULAR LOCATION Does not form aggregates.SUBCELLULAR LOCATION Does not form aggregates.ALTERNATIVE PRODUCTS Expressed in the linker cell just before it dies.DOMAIN The coiled-coil domains in isoform d are important for linker cell death.DISRUPTION PHENOTYPE RNAi-mediated knockdown causes the survival of the linker cell in 16 percent of animals.
created[InstanceEdit:6791590] Weiser, JD
descriptionrecommendedName: fullName evidence="4"Polyglutamine-repeat protein pqn-41 alternativeName: fullName evidence="8"Prion-like-(Q/N-rich)-domain-bearing protein 41
geneNamepqn-41
F53A3.4
identifierC7IVR4
isoformParent
isSequenceChangedFALSE
keywordAlternative splicing
Coiled coil
Cytoplasm
Reference proteome
modified[InstanceEdit:9037114] Weiser, JD
[InstanceEdit:9637257] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
namepqn-41
referenceDatabase[ReferenceDatabase:2] UniProt
secondaryIdentifierPQN41_CAEEL
C7IVR5
C7IVR6
G4RT56
G4RT57
G4RT58
S6FMX9
sequenceLength2049
species[Species:68320] Caenorhabditis elegans
variantIdentifierC7IVR4-4
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