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Details on Person 5'-3' RNA exonuclease activity of XRN2 [nucleoplasm]

Class:IdCatalystActivity:6791580
_displayName5'-3' RNA exonuclease activity of XRN2 [nucleoplasm]
_timestamp2025-01-12 14:56:27
activity[GO_MolecularFunction:12364] 5'-3' RNA exonuclease activity
created[InstanceEdit:6791519] May, Bruce, 2015-08-21
modified[InstanceEdit:6799481] May, Bruce, 2015-09-25
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9689079] Cook, Justin, 2020-05-15
[InstanceEdit:9689079] Cook, Justin, 2020-05-15
[InstanceEdit:9909910] Weiser, Joel, 2024-05-14
[InstanceEdit:9909910] Weiser, Joel, 2024-05-14
[InstanceEdit:9935059] May, Bruce, 2025-01-12
physicalEntity[EntityWithAccessionedSequence:6791205] XRN2 [nucleoplasm] [Homo sapiens]
(catalystActivity)[BlackBoxEvent:6791227] 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA [Homo sapiens]
[BlackBoxEvent:9935299] XRN2 5'-3' exonucleolytically hydrolyzes uncapped RNA [Homo sapiens]
[BlackBoxEvent:9971054] XRN2 degrades downstream RNA fragment, promoting transcription termination [Homo sapiens]
[CatalystActivityReference:9643089] 5'-3' RNA exonuclease activity of XRN2 [nucleoplasm] Gradual processing of the ITS1 from the nucleolus to the cytoplasm during synthesis of the human 18S rRNA
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