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Details on Person Gradual processing of the ITS1 from the nucleolus to the cytoplasm during synthesis of the human 18S rRNA

Class:IdLiteratureReference:6791523
_displayNameGradual processing of the ITS1 from the nucleolus to the cytoplasm during synthesis of the human 18S rRNA
_timestamp2015-08-21 01:57:42
author[Person:6791498] Preti, Milena
[Person:6790875] O'Donohue, Marie-Françoise
[Person:6791559] Montel-Lehry, Nathalie
[Person:6791500] Bortolin-Cavaillé, Marie-Line
[Person:6791174] Choesmel, Valérie
[Person:6790871] Gleizes, Pierre-Emmanuel
created[InstanceEdit:6791519] May, Bruce, 2015-08-21
journalNucleic Acids Res.
pages4709-23
pubMedIdentifier23482395
titleGradual processing of the ITS1 from the nucleolus to the cytoplasm during synthesis of the human 18S rRNA
volume41
year2013
(literatureReference)[BlackBoxEvent:6791222] 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA [Homo sapiens]
[BlackBoxEvent:6791223] 18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol [Homo sapiens]
[CatalystActivityReference:9643089] 5'-3' RNA exonuclease activity of XRN2 [nucleoplasm] Gradual processing of the ITS1 from the nucleolus to the cytoplasm during synthesis of the human 18S rRNA
[CatalystActivityReference:9643798] endoribonuclease activity of NOB1 [cytosol] Both endonucleolytic and exonucleolytic cleavage mediate ITS1 removal during human ribosomal RNA processing
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