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Details on Person TP53 stimulates AIFM2 gene expression

Class:Id	BlackBoxEvent:6791306
_displayName	TP53 stimulates AIFM2 gene expression
_doRelease	TRUE
_timestamp	2016-02-19 18:22:36
authored	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
compartment	[Compartment:17906] mitochondrial outer membrane [Compartment:7660] nucleoplasm
created	[InstanceEdit:6791309] Orlic-Milacic, Marija, 2015-08-20
edited	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
input	[EntityWithAccessionedSequence:6791303] AIFM2 Gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:6791300] AMID is a p53-inducible gene downregulated in tumors
modified	[InstanceEdit:6801450] Orlic-Milacic, Marija, 2015-10-01 [InstanceEdit:6809228] Orlic-Milacic, Marija, 2015-11-09 [InstanceEdit:6809229] Orlic-Milacic, Marija, 2015-11-09 [InstanceEdit:6809233] Orlic-Milacic, Marija, 2015-11-09 [InstanceEdit:6810434] Orlic-Milacic, Marija, 2015-11-16 [InstanceEdit:6810437] Orlic-Milacic, Marija, 2015-11-17 [InstanceEdit:8856076] Orlic-Milacic, Marija, 2016-02-08 [InstanceEdit:8856587] Orlic-Milacic, Marija, 2016-02-10 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TP53 stimulates AIFM2 gene expression
output	[EntityWithAccessionedSequence:5689128] AIFM2 [mitochondrial outer membrane] [Homo sapiens]
precedingEvent	[Reaction:6791302] TP53 binds the AIFM2 gene promoter [Homo sapiens] [Reaction:6799246] CHEK1 phosphorylates TP53 [Homo sapiens] [Reaction:69685] CHEK2 phosphorylates TP53 [Homo sapiens] [Reaction:6805285] PLK3 phosphorylates TP53 [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:6791310] Positive gene expression regulation by 'p-S15,S20-TP53 Tetramer:AIFM2 Gene [nucleoplasm]'
regulationReference	[RegulationReference:9642233] Positive gene expression regulation by 'p-S15,S20-TP53 Tetramer:AIFM2 Gene [nucleoplasm]' AMID is a p53-inducible gene downregulated in tumors
releaseDate	2016-03-23
releaseStatus	NEW
reviewed	[InstanceEdit:8855677] Zaccara, Sara, 2016-02-04 [InstanceEdit:8855680] Inga, Alberto, 2016-02-04
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8861400] R-HSA-6791306.4
summation	[Summation:6791308] TP53 (p53) directly stimulates transcription of the AIFM2 (A...
(hasEvent)	[Pathway:6803204] TP53 Regulates Transcription of Genes Involved in Cytochrome C Release [Homo sapiens]
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No pathways have been reviewed or authored by TP53 stimulates AIFM2 gene expression (6791306)