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Details on Person TP53 binds the AIFM2 gene promoter

Class:Id	Reaction:6791302
_displayName	TP53 binds the AIFM2 gene promoter
_doRelease	TRUE
_timestamp	2017-02-23 15:27:04
authored	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6791297] Orlic-Milacic, Marija, 2015-08-20
edited	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
input	[EntityWithAccessionedSequence:6791303] AIFM2 Gene [nucleoplasm] [Homo sapiens] [Complex:3222171] p-S15,S20-TP53 Tetramer [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:6791300] AMID is a p53-inducible gene downregulated in tumors
modified	[InstanceEdit:6791311] Orlic-Milacic, Marija, 2015-08-20 [InstanceEdit:6799248] Orlic-Milacic, Marija, 2015-09-22 [InstanceEdit:6803268] Orlic-Milacic, Marija, 2015-10-05 [InstanceEdit:6809228] Orlic-Milacic, Marija, 2015-11-09 [InstanceEdit:6809229] Orlic-Milacic, Marija, 2015-11-09 [InstanceEdit:6809233] Orlic-Milacic, Marija, 2015-11-09 [InstanceEdit:6810431] Orlic-Milacic, Marija, 2015-11-16 [InstanceEdit:6810437] Orlic-Milacic, Marija, 2015-11-17 [InstanceEdit:8856076] Orlic-Milacic, Marija, 2016-02-08 [InstanceEdit:8856587] Orlic-Milacic, Marija, 2016-02-10 [InstanceEdit:8979247] Orlic-Milacic, Marija, 2017-02-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TP53 binds the AIFM2 gene promoter
output	[Complex:6791298] p-S15,S20-TP53 Tetramer:AIFM2 Gene [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:6799246] CHEK1 phosphorylates TP53 [Homo sapiens] [Reaction:6799332] ATR phosphorylates TP53 [Homo sapiens] [Reaction:5684887] Activation of CHEK1 at resected DNA DSBs [Homo sapiens] [Reaction:264435] Dissociation of the COP1-p53 complex [Homo sapiens] [Reaction:5693609] ATM phosphorylates TP53 at S15 [Homo sapiens] [Reaction:176116] Recruitment and activation of Chk1 [Homo sapiens] [Reaction:69685] CHEK2 phosphorylates TP53 [Homo sapiens] [Reaction:5693609] ATM phosphorylates TP53 at S15 [Homo sapiens] [Reaction:5683792] p-T68-CHEK2 autophosphorylates [Homo sapiens] [Reaction:264435] Dissociation of the COP1-p53 complex [Homo sapiens] [Reaction:6799332] ATR phosphorylates TP53 [Homo sapiens] [Reaction:6805285] PLK3 phosphorylates TP53 [Homo sapiens] [Reaction:6805470] AMPK phosphorylates TP53 [Homo sapiens] [Reaction:5693609] ATM phosphorylates TP53 at S15 [Homo sapiens] [Reaction:6799332] ATR phosphorylates TP53 [Homo sapiens] [Reaction:6805479] TP53RK phosphorylates TP53 [Homo sapiens]
releaseDate	2016-03-23
releaseStatus	NEW
reviewed	[InstanceEdit:8855677] Zaccara, Sara, 2016-02-04 [InstanceEdit:8855680] Inga, Alberto, 2016-02-04
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8860942] R-HSA-6791302.3
summation	[Summation:6791307] TP53 (p53) binds the promoter of the AIFM2 (AMID) gene, whic...
(hasEvent)	[Pathway:6803204] TP53 Regulates Transcription of Genes Involved in Cytochrome C Release [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:6791306] TP53 stimulates AIFM2 gene expression [Homo sapiens]
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No pathways have been reviewed or authored by TP53 binds the AIFM2 gene promoter (6791302)