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Details on Person Release of NS1 homodimer

Class:Id	Reaction:6791035
_displayName	Release of NS1 homodimer
_doRelease	TRUE
_timestamp	2017-12-01 23:35:37
authored	[InstanceEdit:5146782] Gillespie, ME, 2013-11-18
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6791034] Gillespie, Marc E, 2015-08-17
disease	[Disease:1660558] influenza
edited	[InstanceEdit:5146790] Gillespie, ME, 2013-11-18
input	[Complex:1176067] NS1 homodimer:Importin [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:169116] Influenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3'-end processing machinery [LiteratureReference:3196043] Influenza virus NS1 protein counteracts PKR-mediated inhibition of replication [LiteratureReference:169072] Influenza virus NS1 protein inhibits pre-mRNA splicing and blocks mRNA nucleocytoplasmic transport [LiteratureReference:169092] Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3'end formation of cellular pre-mRNAs
modified	[InstanceEdit:6793638] Gillespie, Marc E, 2015-09-02 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9031715] D'Eustachio, Peter, 2017-12-01 [InstanceEdit:9031726] D'Eustachio, Peter, 2017-12-01 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Release of NS1 homodimer
output	[Complex:169145] NS1 Homodimer [nucleoplasm] [Influenza A virus] [DefinedSet:1176073] Importin [nucleoplasm] [Homo sapiens]
relatedSpecies	[Species:9031716] Influenza A virus
releaseDate	2015-09-22
reviewed	[InstanceEdit:170177] Gale M, Jr, 2004-05-12 19:00:00
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6797009] R-HSA-6791035.4
summation	[Summation:6791031] Once the NS1 homodimer is imported into the nucleus, the imp...
(hasEvent)	[Pathway:168276] NS1 Mediated Effects on Host Pathways [Homo sapiens]
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No pathways have been reviewed or authored by Release of NS1 homodimer (6791035)