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Details on Person The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis

Class:IdLiteratureReference:6790968
_displayNameThe human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis
_timestamp2015-08-16 17:53:17
author[Person:6790974] Zorbas, Christiane
[Person:6790986] Nicolas, Emilien
[Person:6791009] Wacheul, Ludivine
[Person:6790973] Huvelle, Emmeline
[Person:6790991] Heurgué-Hamard, Valérie
[Person:6790983] Lafontaine, Denis L J
created[InstanceEdit:6790964] May, Bruce, 2015-08-16
journalMol. Biol. Cell
pages2080-95
pubMedIdentifier25851604
titleThe human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis
volume26
year2015
(literatureReference)[Reaction:6790982] WBSCR22:TRMT112 methylates guanosine-1639 of 18S rRNA yielding 7-methylguanosine-1639 [Homo sapiens]
[Reaction:6790994] DIMT1 dimethylates adenosine-1850,1851 of 18S rRNA yielding 6-dimethyladenosine-1850,1851 [Homo sapiens]
[RegulationReference:9642606] Requirement by 'PNO1 [nucleoplasm]' The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis
[CatalystActivityReference:9643093] rRNA (adenine-N6,N6-)-dimethyltransferase activity of DIMT1 [nucleoplasm] The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis
[CatalystActivityReference:9643818] rRNA (guanine-N7-)-methyltransferase activity of WBSCR22:TRIMT112 [nucleoplasm] The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis
[Complex:6790980] WBSCR22:TRIMT112 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:6790981] WBSCR22 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:6790984] TRMT112 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:6791001] DIMT1 [nucleoplasm] [Homo sapiens]
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No pathways have been reviewed or authored by The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis (6790968)