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Details on Person The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis
| Class:Id | LiteratureReference:6790968 |
| _displayName | The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis |
| _timestamp | 2015-08-16 17:53:17 |
| author | [Person:6790974] Zorbas, Christiane [Person:6790986] Nicolas, Emilien [Person:6791009] Wacheul, Ludivine [Person:6790973] Huvelle, Emmeline [Person:6790991] Heurgué-Hamard, Valérie [Person:6790983] Lafontaine, Denis L J |
| created | [InstanceEdit:6790964] May, Bruce, 2015-08-16 |
| journal | Mol. Biol. Cell |
| pages | 2080-95 |
| pubMedIdentifier | 25851604 |
| title | The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis |
| volume | 26 |
| year | 2015 |
| (literatureReference) | [Reaction:6790982] WBSCR22:TRMT112 methylates guanosine-1639 of 18S rRNA yielding 7-methylguanosine-1639 [Homo sapiens] [Reaction:6790994] DIMT1 dimethylates adenosine-1850,1851 of 18S rRNA yielding 6-dimethyladenosine-1850,1851 [Homo sapiens] [RegulationReference:9642606] Requirement by 'PNO1 [nucleoplasm]' The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis [CatalystActivityReference:9643093] rRNA (adenine-N6,N6-)-dimethyltransferase activity of DIMT1 [nucleoplasm] The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis [CatalystActivityReference:9643818] rRNA (guanine-N7-)-methyltransferase activity of WBSCR22:TRIMT112 [nucleoplasm] The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis [Complex:6790980] WBSCR22:TRIMT112 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:6790981] WBSCR22 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:6790984] TRMT112 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:6791001] DIMT1 [nucleoplasm] [Homo sapiens] |
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