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Details on Person NOP2 (NSUN1) methylates cytidine-4447 of 28S rRNA yielding 5-methylcytidine-4447

Class:Id	Reaction:6790944
_displayName	NOP2 (NSUN1) methylates cytidine-4447 of 28S rRNA yielding 5-methylcytidine-4447
_doRelease	TRUE
_timestamp	2016-02-19 18:19:36
authored	[InstanceEdit:6790909] May, Bruce, 2015-08-15
catalystActivity	[CatalystActivity:6790916] rRNA (cytosine-C5-)-methyltransferase activity of NOP2 [nucleoplasm]
catalystActivityReference	[CatalystActivityReference:9643783] rRNA (cytosine-C5-)-methyltransferase activity of NOP2 [nucleoplasm] Eukaryotic rRNA Modification by Yeast 5-Methylcytosine-Methyltransferases and Human Proliferation-Associated Antigen p120
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6790913] May, Bruce, 2015-08-15
edited	[InstanceEdit:6790909] May, Bruce, 2015-08-15
goBiologicalProcess	[GO_BiologicalProcess:161509] rRNA methylation
inferredFrom	[Reaction:6790942] NOP2 methylates cytosine-2870 of 25S rRNA yielding 5-methylcytosine-2870 [Saccharomyces cerevisiae]
input	[SimpleEntity:77087] AdoMet [nucleoplasm] [EntityWithAccessionedSequence:74978] nascent pre-rRNA transcript [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:6790931] Eukaryotic rRNA Modification by Yeast 5-Methylcytosine-Methyltransferases and Human Proliferation-Associated Antigen p120
modified	[InstanceEdit:6792486] May, Bruce, 2015-08-24 [InstanceEdit:6793747] May, Bruce, 2015-09-04 [InstanceEdit:6798649] May, Bruce, 2015-09-21 [InstanceEdit:8855037] May, Bruce, 2016-01-30 [InstanceEdit:8856927] May, Bruce, 2016-02-12 [InstanceEdit:8858394] May, Bruce, 2016-02-19 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	NOP2 (NSUN1) methylates cytidine-4447 of 28S rRNA yielding 5-methylcytidine-4447
output	[EntityWithAccessionedSequence:6790943] 28S rRNA containing 5-methylC-4447 [nucleoplasm] [Homo sapiens] [SimpleEntity:77502] AdoHcy [nucleoplasm]
releaseDate	2016-03-23
releaseStatus	NEW
reviewed	[InstanceEdit:8855036] Vincent, Nicholas G, 2016-01-30 [InstanceEdit:8856924] Sharma, Sunny, 2016-02-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8860960] R-HSA-6790944.3
summation	[Summation:6793735] NOP2 methylates the carbon at the 5th position of the cytosi...
(hasEvent)	[Pathway:6790901] rRNA modification in the nucleus and cytosol [Homo sapiens]
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No pathways have been reviewed or authored by NOP2 (NSUN1) methylates cytidine-4447 of 28S rRNA yielding 5-methylcytidine-4447 (6790944)