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Details on Person NOP2 methylates cytosine-2870 of 25S rRNA yielding 5-methylcytosine-2870

Class:Id	Reaction:6790942
_displayName	NOP2 methylates cytosine-2870 of 25S rRNA yielding 5-methylcytosine-2870
_doRelease	TRUE
_timestamp	2017-02-05 02:29:58
authored	[InstanceEdit:6790909] May, Bruce, 2015-08-15
catalystActivity	[CatalystActivity:6790910] rRNA (cytosine-C5-)-methyltransferase activity of NOP2 [nucleoplasm]
catalystActivityReference	[CatalystActivityReference:9643245] rRNA (cytosine-C5-)-methyltransferase activity of NOP2 [nucleoplasm] Eukaryotic rRNA Modification by Yeast 5-Methylcytosine-Methyltransferases and Human Proliferation-Associated Antigen p120
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6790913] May, Bruce, 2015-08-15
edited	[InstanceEdit:6790909] May, Bruce, 2015-08-15
goBiologicalProcess	[GO_BiologicalProcess:161509] rRNA methylation
input	[SimpleEntity:77087] AdoMet [nucleoplasm] [GenomeEncodedEntity:6793689] pre-rRNA [nucleoplasm] [Saccharomyces cerevisiae]
isChimeric	FALSE
literatureReference	[LiteratureReference:6790931] Eukaryotic rRNA Modification by Yeast 5-Methylcytosine-Methyltransferases and Human Proliferation-Associated Antigen p120 [LiteratureReference:6793742] Nop2p is required for pre-rRNA processing and 60S ribosome subunit synthesis in yeast [LiteratureReference:6793721] Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively
modified	[InstanceEdit:6792486] May, Bruce, 2015-08-24 [InstanceEdit:6793747] May, Bruce, 2015-09-04 [InstanceEdit:8855037] May, Bruce, 2016-01-30 [InstanceEdit:8961748] May, Bruce, 2017-02-05 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	NOP2 methylates cytosine-2870 of 25S rRNA yielding 5-methylcytosine-2870
output	[EntityWithAccessionedSequence:6790946] 25S rRNA containing 5-methylC-2870 [nucleoplasm] [Saccharomyces cerevisiae] [SimpleEntity:77502] AdoHcy [nucleoplasm]
releaseDate	2016-03-23
releaseStatus	NEW
reviewed	[InstanceEdit:8855036] Vincent, Nicholas G, 2016-01-30
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:68322] Saccharomyces cerevisiae
stableIdentifier	[StableIdentifier:8860959] R-SCE-6790942.4
summation	[Summation:6793730] NOP2 methylates the carbon at the 5th position of the cytosi...
(inferredFrom)	[Reaction:6790944] NOP2 (NSUN1) methylates cytidine-4447 of 28S rRNA yielding 5-methylcytidine-4447 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9781517] Update Tracker - [Reaction:6790942] NOP2 methylates cytosine-2870 of 25S rRNA yielding 5-methylcytosine-2870 - v60:[add_removeInput]
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