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Details on Person Box H/ACA snoRNP transforms uridine to pseudouridine in pre-rRNA

Class:Id	Reaction:6790905
_displayName	Box H/ACA snoRNP transforms uridine to pseudouridine in pre-rRNA
_doRelease	TRUE
_timestamp	2016-02-19 18:19:34
authored	[InstanceEdit:6790903] May, Bruce, 2015-08-12
catalystActivity	[CatalystActivity:6790900] pseudouridine synthase activity of Box H/ACA snoRNP [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6790904] May, Bruce, 2015-08-15
edited	[InstanceEdit:6790903] May, Bruce, 2015-08-12
goBiologicalProcess	[GO_BiologicalProcess:161845] rRNA pseudouridine synthesis
input	[EntityWithAccessionedSequence:74978] nascent pre-rRNA transcript [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:6790681] snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs [LiteratureReference:6790834] Human box H/ACA pseudouridylation guide RNA machinery [LiteratureReference:6790776] Functionality and substrate specificity of human box H/ACA guide RNAs [LiteratureReference:6792660] RNA pseudouridylation: new insights into an old modification
modified	[InstanceEdit:6793747] May, Bruce, 2015-09-04 [InstanceEdit:8855037] May, Bruce, 2016-01-30 [InstanceEdit:8856927] May, Bruce, 2016-02-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Box H/ACA snoRNP transforms uridine to pseudouridine in pre-rRNA
output	[EntityWithAccessionedSequence:6790694] pre-rRNA containing pseudouridine [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:74992] Dissociation of PTRF:RNA Polymerase I:pre-rRNA complex [Homo sapiens] [Reaction:74993] PTRF binds the paused RNA Polymerase I complex [Homo sapiens]
releaseDate	2016-03-23
releaseStatus	NEW
reviewed	[InstanceEdit:8855036] Vincent, Nicholas G, 2016-01-30 [InstanceEdit:8856924] Sharma, Sunny, 2016-02-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8860954] R-HSA-6790905.2
summation	[Summation:6793701] Box H/ACA snoRNP complexes convert uridine to pseudouridine ...
(hasEvent)	[Pathway:6790901] rRNA modification in the nucleus and cytosol [Homo sapiens]
(precedingEvent)	[Reaction:6790906] EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248 [Homo sapiens]
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No pathways have been reviewed or authored by Box H/ACA snoRNP transforms uridine to pseudouridine in pre-rRNA (6790905)