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Details on Person In melanoma, RAS mutations are accompanied by switching signaling from BRAF to CRAF and disrupted cyclic AMP signaling
| Class:Id | LiteratureReference:6790348 |
| _displayName | In melanoma, RAS mutations are accompanied by switching signaling from BRAF to CRAF and disrupted cyclic AMP signaling |
| _timestamp | 2015-08-10 14:40:13 |
| author | [Person:6790351] Dumaz, Nicolas [Person:6790354] Hayward, Robert [Person:6790352] Martin, Jan [Person:6790349] Ogilvie, Lesley [Person:6790353] Hedley, Douglas [Person:2033086] Curtin, JA [Person:2033065] Bastian, BC [Person:6790355] Springer, Caroline [Person:1497943] Marais, R |
| created | [InstanceEdit:6790350] Rothfels, Karen, 2015-08-10 |
| journal | Cancer Res. |
| pages | 9483-91 |
| pubMedIdentifier | 17018604 |
| title | In melanoma, RAS mutations are accompanied by switching signaling from BRAF to CRAF and disrupted cyclic AMP signaling |
| volume | 66 |
| year | 2006 |
| (literatureReference) | [Reaction:6802908] RAS mutants bind inactive RAF [Homo sapiens] [Reaction:6802924] RAF is phosphorylated downstream of oncogenic RAS [Homo sapiens] [BlackBoxEvent:6803240] Homo- or heterodimerization of RAF downstream of mutant RAS [Homo sapiens] |
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