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Details on Person MOD5 transfers dimethylallyl group to adenosine-37 of tRNA(Ser)

Class:IdReaction:6790167
_displayNameMOD5 transfers dimethylallyl group to adenosine-37 of tRNA(Ser)
_doReleaseTRUE
_timestamp2017-10-17 21:33:17
authored[InstanceEdit:6790132] May, Bruce, 2015-08-08
catalystActivity[CatalystActivity:6790206] tRNA dimethylallyltransferase activity of MOD5 [cytosol]
catalystActivityReference[CatalystActivityReference:9643134] tRNA dimethylallyltransferase activity of MOD5 [cytosol] Competition between a sterol biosynthetic enzyme and tRNA modification in addition to changes in the protein synthesis machinery causes altered nonsense suppression
compartment[Compartment:70101] cytosol
created[InstanceEdit:6790117] May, Bruce, 2015-08-09
edited[InstanceEdit:6790132] May, Bruce, 2015-08-08
goBiologicalProcess[GO_BiologicalProcess:18477] tRNA modification
input[GenomeEncodedEntity:6790186] tRNA(Ser) containing A-37 [cytosol] [Saccharomyces cerevisiae]
[SimpleEntity:191324] DMAPP [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:6790120] Isolation and characterization of MOD5, a gene required for isopentenylation of cytoplasmic and mitochondrial tRNAs of Saccharomyces cerevisiae
[LiteratureReference:6790141] Competition between a sterol biosynthetic enzyme and tRNA modification in addition to changes in the protein synthesis machinery causes altered nonsense suppression
[LiteratureReference:6790124] Plasticity and diversity of tRNA anticodon determinants of substrate recognition by eukaryotic A37 isopentenyltransferases
modified[InstanceEdit:6792692] May, Bruce, 2015-08-25
[InstanceEdit:6806694] May, Bruce, 2015-10-24
[InstanceEdit:9026194] D'Eustachio, Peter, 2017-10-17
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameMOD5 transfers dimethylallyl group to adenosine-37 of tRNA(Ser)
output[GenomeEncodedEntity:6790196] tRNA(Ser) containing isopentenylA-37 [cytosol] [Saccharomyces cerevisiae]
[SimpleEntity:111294] PPi [cytosol]
releaseDate2015-09-22
releaseStatusNEW
reviewed[InstanceEdit:6792690] Motorin, Yuri, 2015-08-25
[InstanceEdit:6806693] Jarrous, Nayef, 2015-10-24
reviewStatus[ReviewStatus:9821382] five stars
species[Species:68322] Saccharomyces cerevisiae
stableIdentifier[StableIdentifier:6797002] R-SCE-6790167.5
summation[Summation:6790220] MOD5 transfers a dimethylallyl group (isopentenyl group) fro...
(inferredFrom)[Reaction:6784462] TRIT1 transfers dimethylallyl group to adenosine-37 of tRNAs [Homo sapiens]
(updatedInstance)[_UpdateTracker:9780259] Update Tracker - [Reaction:6790167] MOD5 transfers dimethylallyl group to adenosine-37 of tRNA(Ser) - v63:[add_removeInput]
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