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Details on Person Interleukin-13 receptor alpha subunit (IL13RA1) binds Interl...
| Class:Id | Summation:6788349 |
|---|---|
| _displayName | Interleukin-13 receptor alpha subunit (IL13RA1) binds Interl... |
| _timestamp | 2015-09-14 14:00:25 |
| created | [InstanceEdit:6788305] Jupe, Steve, 2015-07-20 |
| literatureReference | [LiteratureReference:449676] Cloning of the human IL-13R alpha1 chain and reconstitution with the IL4R alpha of a functional IL-4/IL-13 receptor complex |
| modified | [InstanceEdit:6797572] Jupe, Steve, 2015-09-14 |
| text | Interleukin-13 receptor alpha subunit (IL13RA1) binds Interleukin-13 (IL13) with a relatively low affinity, but when paired with Interleukin-4 receptor subunit alpha (IL4R), binds with much higher affinity (Kd = 400 pmol/L) and forms a functional IL13 receptor that is capable of signaling (Miloux et al. 1997). This type II IL13 receptor complex is also the alternative type II receptor for IL4. |
| (summation) | [Reaction:6786114] IL13:IL13RA:TYK2 binds IL4R:JAK2 [Homo sapiens] |
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No pathways have been reviewed or authored by Interleukin-13 receptor alpha subunit (IL13RA1) binds Interl... (6788349)
