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Details on Person In monocytes and macrophages Interleukin-13 (IL13) enhances ...
| Class:Id | Summation:6788328 |
|---|---|
| _displayName | In monocytes and macrophages Interleukin-13 (IL13) enhances ... |
| _timestamp | 2015-09-14 14:00:20 |
| created | [InstanceEdit:6788305] Jupe, Steve, 2015-07-20 |
| literatureReference | [LiteratureReference:6789330] Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells [LiteratureReference:6789345] The role of IL-13 and its receptor in allergy and inflammatory responses [LiteratureReference:6789365] IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells |
| modified | [InstanceEdit:6789329] Jupe, Steve, 2015-07-30 [InstanceEdit:6797292] Jupe, Steve, 2015-09-07 [InstanceEdit:6797572] Jupe, Steve, 2015-09-14 |
| text | In monocytes and macrophages Interleukin-13 (IL13) enhances the expression of many members of the integrin family including Integrin alpha M (ITGAM, CD11b), Integrin alpha-X (ITGAX, CD11c), Integrin beta 2 (ITGB2, CD18) and Integrin beta 1 (ITGB1, CD29) (Zurawski & de Vries 1994), MHC class II and ow affinity immunoglobulin epsilon Fc receptor (FCER2, CD23) expression (de Vries 1998). In endothelial cells IL13 induces expression of Vascular cell adhesion protein 1 (VCAM1), which is important in the recruitment of eosinophils (Bochner et al. 1995). |
| (summation) | [BlackBoxEvent:6788346] Expression of IL13-upregulated plasma membrane proteins [Homo sapiens] |
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