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Details on Person Flt3 ligand induces tyrosine phosphorylation of gab1 and gab2 and their association with shp-2, grb2, and PI3 kinase

Class:IdLiteratureReference:6786770
_displayNameFlt3 ligand induces tyrosine phosphorylation of gab1 and gab2 and their association with shp-2, grb2, and PI3 kinase
_timestamp2015-07-10 16:19:50
author[Person:6786768] Zhang, S
[Person:6786774] Broxmeyer, H E
created[InstanceEdit:6786759] Jupe, Steve, 2015-07-10
journalBiochem. Biophys. Res. Commun.
modified[InstanceEdit:6786892] Jupe, Steve, 2015-07-10
pages195-9
pubMedIdentifier11027663
titleFlt3 ligand induces tyrosine phosphorylation of gab1 and gab2 and their association with shp-2, grb2, and PI3 kinase
volume277
year2000
(literatureReference)[Summation:6786777] FLT3 is a member of the Class III Receptor Tyrosine Kinase F...
[BlackBoxEvent:9606621] Gab2 in Active Flt3:Grb2:Gab2 is phosphorylated [Mus musculus]
[BlackBoxEvent:9606622] GAB2 in Active FLT3:GRB2:GAB2 is phosphorylated [Homo sapiens]
[Reaction:9606623] Active Flt3:Grb2 binds Gab2 [Mus musculus]
[Reaction:9606624] Active FLT3:GRB2 binds GAB2 [Homo sapiens]
[BlackBoxEvent:9606784] Active FLT3:GRB2:p-Y-GAB2 binds PTPN11 [Homo sapiens]
[BlackBoxEvent:9606789] Active Flt3:Grb2:p-Y-Gab2 binds Ptpn11 [Mus musculus]
[Reaction:9607224] Active FLT3:GRB2:p-Y-GAB2 binds PIK3R1 [Homo sapiens]
[Reaction:9607226] Active Flt3:Grb2:p-Y-Gab2 binds Pik3r1 [Mus musculus]
[Reaction:9698000] FLT3 mutants:GRB2 bind GAB2 [Homo sapiens]
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