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Details on Person FLT3LG dimer:FLT3 [plasma membrane]

Class:IdComplex:6786754
_displayNameFLT3LG dimer:FLT3 [plasma membrane]
_timestamp2016-02-19 18:12:33
compartment[Compartment:876] plasma membrane
created[InstanceEdit:6786759] Jupe, Steve, 2015-07-10
hasComponent
includedLocation[Compartment:984] extracellular region
isChimericFALSE
modified[InstanceEdit:6786892] Jupe, Steve, 2015-07-10
[InstanceEdit:8854731] Jupe, Steve, 2016-01-28
nameFLT3LG dimer:FLT3
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8859067] R-HSA-6786754.1
(hasComponent)[Complex:8854716] FLT3LG dimer:FLT3 dimer [plasma membrane] [Homo sapiens]
[Complex:9695796] FLT3LG dimer:FLT3:FLT3-binding type I TKIs [plasma membrane] [Homo sapiens]
(input)[Reaction:8854736] FLT3LG dimer:FLT3 binds FLT3 [Homo sapiens]
[Reaction:9695828] FLT3 binds type I TKI [Homo sapiens]
(normalEntity)[EntityFunctionalStatus:9702571] loss_of_function of KW2449-resistant FLT3 mutants [plasma membrane]
[EntityFunctionalStatus:9702575] loss_of_function of semaxanib-resistant FLT3 mutants [plasma membrane]
[EntityFunctionalStatus:9702584] loss_of_function of crenolanib-resistant FLT3 mutants [plasma membrane]
[EntityFunctionalStatus:9702588] loss_of_function of gilteritinib-resistant FLT3 mutants [plasma membrane]
[EntityFunctionalStatus:9702594] loss_of_function of lestaurtinib-resistant FLT3 mutants [plasma membrane]
[EntityFunctionalStatus:9702602] loss_of_function of midostaurin-resistant FLT3 mutants [plasma membrane]
[EntityFunctionalStatus:9702996] loss_of_function of linifanib-resistant FLT3 mutants [plasma membrane]
[EntityFunctionalStatus:9703005] loss_of_function of tamatinib-resistant FLT3 mutants [plasma membrane]
(output)[Reaction:6786789] FLT3LG dimer binds FLT3 [Homo sapiens]
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No pathways have been reviewed or authored by FLT3LG dimer:FLT3 [plasma membrane] (6786754)