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Details on Person DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA

Class:Id	Reaction:6786720
_displayName	DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA
_doRelease	TRUE
_timestamp	2024-08-02 16:00:34
authored	[InstanceEdit:6786719] Jassal, Bijay, 2015-07-10
catalystActivity	[CatalystActivity:6786714] trans-2-enoyl-CoA reductase (NADPH) activity of DECR2 [peroxisomal membrane]
catalystActivityReference	[CatalystActivityReference:9914129] trans-2-enoyl-CoA reductase (NADPH) activity of DECR2 [peroxisomal membrane] Characterisation of human peroxisomal 2,4-dienoyl-CoA reductase
compartment	[Compartment:17951] peroxisomal matrix [Compartment:17947] peroxisomal membrane
created	[InstanceEdit:6786719] Jassal, Bijay, 2015-07-10
edited	[InstanceEdit:6786719] Jassal, Bijay, 2015-07-10
input	[SimpleEntity:113602] NADPH [peroxisomal matrix] [SimpleEntity:193465] H+ [peroxisomal matrix] [SimpleEntity:9914117] (2E,4E)-dienoyl-CoA [peroxisomal matrix]
internalReviewed	[InstanceEdit:9914192] D'Eustachio, Peter, 2024-06-21 [InstanceEdit:9914195] D'Eustachio, Peter, 2024-06-21
isChimeric	FALSE
literatureReference	[LiteratureReference:6786718] Characterisation of human peroxisomal 2,4-dienoyl-CoA reductase [LiteratureReference:6786716] Studies of human 2,4-dienoyl CoA reductase shed new light on peroxisomal β-oxidation of unsaturated fatty acids
modified	[InstanceEdit:6786726] Jassal, Bijay, 2015-07-10 [InstanceEdit:6797579] Jassal, Bijay, 2015-09-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9914142] D'Eustachio, Peter, 2024-06-20 [InstanceEdit:9914193] D'Eustachio, Peter, 2024-06-21 [InstanceEdit:9914196] D'Eustachio, Peter, 2024-06-21 [InstanceEdit:9917351] D'Eustachio, Peter, 2024-08-02
name	DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA a (2E,4E)-dienoyl-CoA + H(+) + NADPH => a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)
output	[SimpleEntity:389556] NADP+ [peroxisomal matrix] [SimpleEntity:9914123] 4,5-saturated-(3E)-enoyl-CoA(4-) [peroxisomal matrix]
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2015-12-15
releaseStatus	NEW
reviewed	[InstanceEdit:6797578] D'Eustachio, Peter, 2015-09-14 [InstanceEdit:9917333] Hill, David P, 2024-08-02
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6812448] R-HSA-6786720.3
structureModified	[InstanceEdit:9914142] D'Eustachio, Peter, 2024-06-20
summation	[Summation:6786724] Saturated and unsaturated fats can undergo beta-oxidation in...
(hasEvent)	[Pathway:390247] Beta-oxidation of very long chain fatty acids [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9919428] Update Tracker - [Reaction:6786720] DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA - v90:[add_removeInput, add_removeOutput, modifyText]
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