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Details on Person KIAA1456 (TRM9L) methylates 5-carboxymethyluridine in tRNA yielding 5-methoxycarbonylmethyluridine

Class:Id	Reaction:6786567
_displayName	KIAA1456 (TRM9L) methylates 5-carboxymethyluridine in tRNA yielding 5-methoxycarbonylmethyluridine
_doRelease	TRUE
_timestamp	2015-10-24 03:31:25
authored	[InstanceEdit:6785729] May, Bruce, 2015-06-30
catalystActivity	[CatalystActivity:6786625] tRNA methyltransferase activity of KIAA1456 [cytoplasm]
catalystActivityReference	[CatalystActivityReference:9643266] tRNA methyltransferase activity of KIAA1456 [cytoplasm] A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-α
compartment	[Compartment:459] cytoplasm
created	[InstanceEdit:6786517] May, Bruce, 2015-07-09
edited	[InstanceEdit:6785729] May, Bruce, 2015-06-30
goBiologicalProcess	[GO_BiologicalProcess:18477] tRNA modification
input	[GenomeEncodedEntity:6786496] tRNA containing 5-carboxymethylU-34 [cytoplasm] [Homo sapiens] [SimpleEntity:5279190] AdoMet [cytoplasm]
isChimeric	FALSE
literatureReference	[LiteratureReference:6786578] A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-α
modified	[InstanceEdit:6787709] May, Bruce, 2015-07-15 [InstanceEdit:6790222] May, Bruce, 2015-08-09 [InstanceEdit:6792692] May, Bruce, 2015-08-25 [InstanceEdit:6806694] May, Bruce, 2015-10-24 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	KIAA1456 (TRM9L) methylates 5-carboxymethyluridine in tRNA yielding 5-methoxycarbonylmethyluridine
output	[GenomeEncodedEntity:6786605] tRNA containing 5-methoxycarbonylmethylU-34 [cytoplasm] [Homo sapiens] [SimpleEntity:5278409] AdoHcy [cytoplasm]
releaseDate	2015-09-22
releaseStatus	NEW
reviewed	[InstanceEdit:6790491] Levinger, Louis, 2015-08-10 [InstanceEdit:6792690] Motorin, Yuri, 2015-08-25 [InstanceEdit:6806693] Jarrous, Nayef, 2015-10-24
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:6796986] R-HSA-6786567.4
summation	[Summation:6786530] KIAA1456 (TRM9L, hTRM9L) transfers a methyl group from S-ade...
(hasEvent)	[Pathway:6782315] tRNA modification in the nucleus and cytosol [Homo sapiens]
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