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Details on Person p-Y641-STAT6 dimer [nucleoplasm]

Class:Id	Complex:6786281
_displayName	p-Y641-STAT6 dimer [nucleoplasm]
_timestamp	2016-07-15 23:49:48
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6786277] Jupe, Steve, 2015-07-06
hasComponent	[EntityWithAccessionedSequence:6786279] p-Y641-STAT6 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:6786279] p-Y641-STAT6 [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:6786314] Jupe, Steve, 2015-07-06 [InstanceEdit:8879177] Wu, G, 2016-07-15
name	p-Y641-STAT6 dimer
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8904462] R-HSA-6786281.1
(activeUnit)	[PositiveGeneExpressionRegulation:9976145] Positive gene expression regulation by 'MLL1:MEN1:p-Y641-STAT6:p-S243-NFATC2:Notch1,2 Coactivator:GATA3 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9977763] Positive gene expression regulation by 'GATA3:YY1:ETS1:POU2F1:POU2F2:BATF:p-Y641-STAT6:SATB1:IRF4:SMARCA4:RAD50 gene [nucleoplasm]'
(hasComponent)	[Complex:9942244] BATF:IRF4:STAT3:STAT6:IL4 gene [nucleoplasm] [Homo sapiens] [Complex:9976109] MLL1:MEN1:p-Y641-STAT6:p-S243-NFATC2:Notch1,2 Coactivator:GATA3 gene [nucleoplasm] [Homo sapiens] [Complex:9977761] GATA3:YY1:ETS1:POU2F1:POU2F2:BATF:p-Y641-STAT6:SATB1:IRF4:SMARCA4:RAD50 gene [nucleoplasm] [Homo sapiens]
(hasMember)	[DefinedSet:6788575] p-Y705-STAT3 dimer, p-Y641-STAT6 dimer [nucleoplasm] [Homo sapiens] [DefinedSet:6788618] p-Y701-STAT1 dimer,p-Y705-STAT3 dimer,p-Y641-STAT6 dimer [nucleoplasm] [Homo sapiens]
(input)	[Reaction:9946883] BATF:IRF4, STAT3, and STAT6 bind the IL4 gene [Homo sapiens] [Reaction:9976117] STAT6, NFATC2 (NFAT1), and NICD1,2 bind the GATA3 gene and cause displacement of repressor complexes (PRC1, RBPJ:NCOR) by activator complexes (MLL1, RBPJ:NICD1,2) [Homo sapiens] [Reaction:9977764] GATA3, YY1, ETS1, POU2F1 (OCT1), POU2F2 (OCT2), BATF, SATB1, IRF4, SMARCA4, and STAT6 bind the Locus Control Region (LCR) in the RAD50 gene [Homo sapiens]
(physicalEntity)	[PhysicalEntityCellType:9966285] p-Y641-STAT6 dimer [nucleoplasm] in T follicular helper cell (Tfh)
(regulator)	[PositiveGeneExpressionRegulation:6787779] Positive gene expression regulation by 'p-Y641-STAT6 dimer [nucleoplasm]' [PositiveRegulation:6793997] Positive regulation by 'p-Y641-STAT6 dimer [nucleoplasm]' [PositiveGeneExpressionRegulation:6794000] Positive gene expression regulation by 'p-Y641-STAT6 dimer [nucleoplasm]' [PositiveRegulation:6794002] Positive regulation by 'p-Y641-STAT6 dimer [nucleoplasm]'
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No pathways have been reviewed or authored by p-Y641-STAT6 dimer [nucleoplasm] (6786281)