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Details on Person STAT3,STAT6 bind p-Y-IL4R

Class:Id	Reaction:6786124
_displayName	STAT3,STAT6 bind p-Y-IL4R
_doRelease	TRUE
_timestamp	2016-09-02 11:52:17
authored	[InstanceEdit:6785864] Jupe, Steve, 2015-07-01
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:6786052] Jupe, Steve, 2015-07-03
edited	[InstanceEdit:8937485] Jupe, Steve, 2016-09-02
input	[Complex:6786061] IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1 [plasma membrane] [Homo sapiens] [DefinedSet:6786055] STAT3,STAT6 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:6786079] An interleukin-4-induced transcription factor: IL-4 Stat [LiteratureReference:6786116] Components of a Stat recognition code: evidence for two layers of molecular selectivity [LiteratureReference:6786084] Mutational analysis of the STAT6 SH2 domain [LiteratureReference:6786094] Aberrant Stat3 signaling by interleukin-4 in malignant glioma cells: involvement of IL-13Ralpha2 [LiteratureReference:6785892] IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages
modified	[InstanceEdit:6786277] Jupe, Steve, 2015-07-06 [InstanceEdit:6788583] Jupe, Steve, 2015-07-23 [InstanceEdit:6797418] Jupe, Steve, 2015-09-10 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8937483] Jupe, Steve, 2016-09-02 [InstanceEdit:8937493] Jupe, Steve, 2016-09-02 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	STAT3,STAT6 bind p-Y-IL4R
output	[Complex:6786077] IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1:STAT3,STAT6 [plasma membrane] [Homo sapiens]
precedingEvent	[BlackBoxEvent:6786096] IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated [Homo sapiens] [BlackBoxEvent:6786058] JAK1 binds IL4R in IL4-bound IL4R1 [Homo sapiens]
releaseDate	2016-12-12
reviewed	[InstanceEdit:8937491] Leibovich, Samuel, 2016-09-02
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8912667] R-HSA-6786124.2
summation	[Summation:6786123] Signal transducer and activator of transcription 6 (STAT6) b...
(hasEvent)	[Pathway:6785807] Interleukin-4 and Interleukin-13 signaling [Homo sapiens]
(precedingEvent)	[Reaction:6786095] JAK1 phosphorylates STAT3,STAT6 [Homo sapiens]
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No pathways have been reviewed or authored by STAT3,STAT6 bind p-Y-IL4R (6786124)