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Query author contributions in Reactome

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Details on Person Interleukin-13 receptor subunit alpha-1 (IL13RA1), with asso...

Class:IdSummation:6786071
_displayNameInterleukin-13 receptor subunit alpha-1 (IL13RA1), with asso...
_timestamp2015-09-10 16:04:25
created[InstanceEdit:6786052] Jupe, Steve, 2015-07-03
literatureReference[LiteratureReference:6785787] Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common gamma chain shared by receptors for interleukins 2, 4, 7, 9, and 15
[LiteratureReference:6785857] cDNA cloning and characterization of the human interleukin 13 receptor alpha chain
[LiteratureReference:6788327] Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor
[LiteratureReference:450011] Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system
modified[InstanceEdit:6797418] Jupe, Steve, 2015-09-10
textInterleukin-13 receptor subunit alpha-1 (IL13RA1), with associated Non-receptor tyrosine-protein kinase 2 (TYK2), binds the IL4:IL4R:JAK2 complex to form the ligand-bound Type II IL4 receptor complex (IL4R2). IL4R2 is predominantly expressed on the surface of non-hematopoietic cells. It is also a receptor for Interleukin-13 (IL13) (Obiri et al. 1995, Aman et al. 1996, Hilton et al. 1996). Crystal structures of the IL4:IL4R:IL13RA1 and IL13:IL4R:IL13RA1 complexes have been determined (LaPorte et al. 2008).
(summation)[Reaction:6786070] IL4:IL4R:JAK2 binds IL13RA1:TYK2 [Homo sapiens]
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