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Details on Person IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1 [plasma membrane]

Class:Id	Complex:6786061
_displayName	IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1 [plasma membrane]
_timestamp	2016-07-15 23:50:10
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:6786052] Jupe, Steve, 2015-07-03
hasComponent	[EntityWithAccessionedSequence:451921] p-Y-JAK1 [cytosol] [Homo sapiens] [Complex:6786086] IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3 [plasma membrane] [Homo sapiens] [Complex:6786122] IL4:p-Y-IL4R:JAK2 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:447110] IL4 [extracellular region] [Homo sapiens] [Complex:6786120] p-Y-IL4R:JAK2 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:210620] JAK2 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:6786087] p-Y-IL4R [plasma membrane] [Homo sapiens] [Complex:6786057] p-Y-IL2RG:JAK3 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:451893] JAK3 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:6786103] p-Y-IL2RG [plasma membrane] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15
name	IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8913268] R-HSA-6786061.1
(hasComponent)	[Complex:6786077] IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1:STAT3,STAT6 [plasma membrane] [Homo sapiens] [Complex:6786088] IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1:p-Y705-STAT3,p-Y641-STAT6 [plasma membrane] [Homo sapiens]
(hasMember)	[DefinedSet:6788586] Type I IL4 receptor with active JAK1, Type I IL13 receptor with active JAK1 [plasma membrane] [Homo sapiens]
(input)	[Reaction:6786124] STAT3,STAT6 bind p-Y-IL4R [Homo sapiens]
(output)	[BlackBoxEvent:6786072] p-Y705-STAT3,p-Y641-STAT6 dissociate [Homo sapiens] [BlackBoxEvent:6786096] IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated [Homo sapiens]
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No pathways have been reviewed or authored by IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1 [plasma membrane] (6786061)