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Details on Person JAK1 binds IL4R in IL4-bound IL4R1

Class:IdBlackBoxEvent:6786058
_displayNameJAK1 binds IL4R in IL4-bound IL4R1
_doReleaseTRUE
_timestamp2016-09-02 11:51:48
authored[InstanceEdit:6785864] Jupe, Steve, 2015-07-01
compartment[Compartment:70101] cytosol
[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:6786052] Jupe, Steve, 2015-07-03
edited[InstanceEdit:8937485] Jupe, Steve, 2016-09-02
input[Complex:6786078] IL4:IL4R:JAK2:IL2RG:JAK3 [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:451898] JAK1 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:6785892] IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages
[LiteratureReference:6785889] IL-13 signal transduction in human monocytes: phosphorylation of receptor components, association with Jaks, and phosphorylation/activation of Stats
modified[InstanceEdit:6797418] Jupe, Steve, 2015-09-10
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:8937483] Jupe, Steve, 2016-09-02
[InstanceEdit:8937493] Jupe, Steve, 2016-09-02
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameJAK1 binds IL4R in IL4-bound IL4R1
output[Complex:6786090] IL4:IL4R:JAK2:IL2RG:JAK3:JAK1 [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2016-12-12
reviewed[InstanceEdit:8937491] Leibovich, Samuel, 2016-09-02
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8881408] R-HSA-6786058.2
summation[Summation:6786067] In human blood monocytes, where the type I interleukin-4 (IL...
(hasEvent)[Pathway:6785807] Interleukin-4 and Interleukin-13 signaling [Homo sapiens]
(precedingEvent)[BlackBoxEvent:6786096] IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated [Homo sapiens]
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