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Details on Person In human peripheral blood monocytes IL4 and IL13 significant...

Class:IdSummation:6785802
_displayNameIn human peripheral blood monocytes IL4 and IL13 significant...
_timestamp2015-09-07 15:04:24
created[InstanceEdit:6785864] Jupe, Steve, 2015-07-01
literatureReference[LiteratureReference:6785892] IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages
[LiteratureReference:6789484] Gene expression alterations of human peripheral blood monocytes induced by medium-term treatment with the TH2-cytokines interleukin-4 and -13
[LiteratureReference:6789526] αMßâ‚‚ integrin activation prevents alternative activation of human and murine macrophages and impedes foam cell formation
[LiteratureReference:6789343] Interleukin-13 stimulates the transcription of the human alpha2(I) collagen gene in human dermal fibroblasts
modified[InstanceEdit:6788305] Jupe, Steve, 2015-07-20
[InstanceEdit:6789519] Jupe, Steve, 2015-07-31
[InstanceEdit:6797274] Jupe, Steve, 2015-09-07
[InstanceEdit:6797292] Jupe, Steve, 2015-09-07
textIn human peripheral blood monocytes IL4 and IL13 significantly upregulate the levels of several extracellular proteins involved in inflammatory resolution including fibronectin (FN1), coagulation factor XIII (FXIII), annexin 1 (ANXA1), collagen type 1 alpha 2 (COL1A2), laminin alpha-5 (LAMA5) and C-C motif chemokine 22 (CCL22) (Chaitidis et al. 2005, Jinnin et al. 2004, Yakubenko et al. 2011).
(summation)[BlackBoxEvent:6785895] Expression of IL4, IL13-upregulated extracellular proteins [Homo sapiens]
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