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Details on Person Mbtps1,2 cleaves Creb3l3 to Creb3l3(1-?) and Creb3l3(?-461)

Class:Id	BlackBoxEvent:6784684
_displayName	Mbtps1,2 cleaves Creb3l3 to Creb3l3(1-?) and Creb3l3(?-461)
_doRelease	TRUE
_timestamp	2020-08-21 12:41:46
authored	[InstanceEdit:6784714] Sanchis, Alba, 2015-05-12
catalystActivity	[CatalystActivity:6784914] metalloendopeptidase activity of Mbtps1,2 [endoplasmic reticulum membrane]
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:6784679] Sanchis, Alba, 2015-06-22
edited	[InstanceEdit:6784679] Sanchis, Alba, 2015-06-22
input	[EntityWithAccessionedSequence:6784660] Creb3l3 [endoplasmic reticulum membrane] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:6784667] The role of CREB-H transcription factor in triglyceride metabolism [LiteratureReference:6784687] Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response [LiteratureReference:6784634] Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8979324] D'Eustachio, Peter, 2017-02-24 [InstanceEdit:8980654] Jupe, Steve, 2017-02-28 [InstanceEdit:8981141] Jassal, Bijay, 2017-03-01 [InstanceEdit:9697789] Jassal, Bijay, 2020-08-21 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Mbtps1,2 cleaves Creb3l3 to Creb3l3(1-?) and Creb3l3(?-461)
output	[EntityWithAccessionedSequence:6784697] Creb3l3(1-?) [cytosol] [Mus musculus] [EntityWithAccessionedSequence:6784689] Creb3l3(?-479) [endoplasmic reticulum membrane] [Mus musculus]
releaseDate	2016-06-15
reviewed	[InstanceEdit:8868240] D'Eustachio, Peter, 2016-04-20
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:8918108] R-MMU-6784684.3
summation	[Summation:6784657] Creb3l3 is a transcription factor that is highly and selecti...
(inferredFrom)	[Reaction:6784620] MBTPS1,2 cleaves CREB3L3 to CREB3L3(1-?) and CREB3L3(?-461) [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9776673] Update Tracker - [BlackBoxEvent:6784684] Mbtps1,2 cleaves Creb3l3 to Creb3l3(1-?) and Creb3l3(?-461) - v74:[add_removeCatalystActivity]
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