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Details on Person Proline dehydrogenase 2 (PRODH2) is a hydroxyproline dehydrogenase (HYPDH) and molecular target for treating primary hyperoxaluria

Class:Id	LiteratureReference:6784230
_displayName	Proline dehydrogenase 2 (PRODH2) is a hydroxyproline dehydrogenase (HYPDH) and molecular target for treating primary hyperoxaluria
_timestamp	2015-06-18 21:54:55
author	[Person:6784237] Summitt, Candice B [Person:6784235] Johnson, Lynnette C [Person:6784231] J�nsson, Thomas J [Person:6784227] Parsonage, Derek [Person:389835] Holmes, Ross P [Person:389830] Lowther, W Todd
created	[InstanceEdit:6784239] D'Eustachio, Peter, 2015-06-18
journal	Biochem. J.
pages	273-81
pubMedIdentifier	25697095
title	Proline dehydrogenase 2 (PRODH2) is a hydroxyproline dehydrogenase (HYPDH) and molecular target for treating primary hyperoxaluria
volume	466
year	2015
(literatureReference)	[Complex:6784228] PRODH2:FAD [mitochondrial inner membrane] [Homo sapiens] [Complex:6784240] PRODH2 dimer [mitochondrial inner membrane] [Homo sapiens] [Reaction:6784224] PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate [Homo sapiens] [Reaction:8955817] PRODH2 oxidises HPRO to 1PYR-3OH-5COOH [Homo sapiens] [CatalystActivityReference:9643872] proline dehydrogenase activity of PRODH2 dimer [mitochondrial inner membrane] Proline dehydrogenase 2 (PRODH2) is a hydroxyproline dehydrogenase (HYPDH) and molecular target for treating primary hyperoxaluria
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