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Details on Person tRNA:XPOT:RAN:GTP translocates from the nucleus to the cytosol
Class:Id Reaction:6783483
_displayName tRNA:XPOT:RAN:GTP translocates from the nucleus to the cytosol
_doRelease TRUE
_timestamp 2015-10-24 03:50:04
authored [InstanceEdit:6783442] May, Bruce, 2015-06-15
catalystActivity [CatalystActivity:450099] structural constituent of nuclear pore activity of Nuclear Pore Complex (NPC) [nuclear envelope]
catalystActivityReference [CatalystActivityReference:9643944] structural constituent of nuclear pore activity of Nuclear Pore Complex (NPC) [nuclear envelope] Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase
compartment [Compartment:70101] cytosol [Compartment:7660] nucleoplasm [Compartment:13231] nuclear envelope
created [InstanceEdit:6783459] May, Bruce, 2015-06-15
edited [InstanceEdit:6783442] May, Bruce, 2015-06-15
goBiologicalProcess [GO_BiologicalProcess:18494] tRNA export from nucleus
input [Complex:6783450] tRNA:XPOT:RAN:GTP [nucleoplasm] [Homo sapiens]
isChimeric FALSE
literatureReference [LiteratureReference:6783498] Identification of a tRNA-specific nuclear export receptor [LiteratureReference:6783509] Identification of a nuclear export receptor for tRNA [LiteratureReference:6783504] Steady-state nuclear localization of exportin-t involves RanGTP binding and two distinct nuclear pore complex interaction domains [LiteratureReference:6783472] Interaction of immobilized human exportin-t with calf liver tRNA [LiteratureReference:6784571] Exportin t and Exportin 5: tRNA and miRNA biogenesis - and beyond
modified [InstanceEdit:6784528] May, Bruce, 2015-06-20 [InstanceEdit:6784590] May, Bruce, 2015-06-21 [InstanceEdit:6785471] May, Bruce, 2015-06-28 [InstanceEdit:6785482] May, Bruce, 2015-06-28 [InstanceEdit:6786890] May, Bruce, 2015-07-10 [InstanceEdit:6788634] May, Bruce, 2015-07-23 [InstanceEdit:6788720] May, Bruce, 2015-07-24 [InstanceEdit:6790493] May, Bruce, 2015-08-10 [InstanceEdit:6792692] May, Bruce, 2015-08-25 [InstanceEdit:6806694] May, Bruce, 2015-10-24 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name tRNA:XPOT:RAN:GTP translocates from the nucleus to the cytosol
output [SimpleEntity:29372] Pi [cytosol] [Complex:206617] RAN:GDP [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:6783484] XPOT [cytosol] [Homo sapiens] [DefinedSet:6785476] processed tRNA [cytosol] [Homo sapiens]
precedingEvent
releaseDate 2015-09-22
releaseStatus NEW
reviewed [InstanceEdit:6790491] Levinger, Louis, 2015-08-10 [InstanceEdit:6792690] Motorin, Yuri, 2015-08-25 [InstanceEdit:6806693] Jarrous, Nayef, 2015-10-24
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:6796958] R-HSA-6783483.4
summation [Summation:6784549] The nuclear export receptor XPOT (Exportin-t) interacts with...
(hasEvent) [Pathway:6784531] tRNA processing in the nucleus [Homo sapiens]
(precedingEvent) [Reaction:6782264] CTU1:CTU2:URM1 thiolates uridine-34 in tRNAs [Homo sapiens] [Reaction:6782296] DUS2:EPRS reduces uridine to dihydrouridine in tRNAs [Homo sapiens] [Reaction:6782434] THG1L transfers GMP to 5' end of tRNA(His) [Homo sapiens] [Reaction:6782443] QTRT1:QTRTD1 exchanges guanine for queuine at guanosine-34 of tRNA(Asn),tRNA(Asp),tRNA(His),tRNA(Tyr) yielding queuosine-34 tRNA(Asn),tRNA(Asp),tRNA(His),tRNA(Tyr) [Homo sapiens] [Reaction:6784462] TRIT1 transfers dimethylallyl group to adenosine-37 of tRNAs [Homo sapiens] [Reaction:6786500] ALKBH8 methylates 5-carboxymethyluridine-34 in tRNA(Arg) and tRNA(Glu) yielding 5-methoxycarbonylmethyluridine-34 [Homo sapiens] [Reaction:6786501] TRMT11:TRMT112 methylates guanosine-10 in tRNA [Homo sapiens] [BlackBoxEvent:6786571] CDKAL1:4Fe-4S methylthiolates N6-threonylcarbamoyladenosine-37 in tRNA yielding 2-methylthio-N6-threonylcarbamoyladenosine-37 [Homo sapiens] [Reaction:6788707] TRMT44 2'-O-methylates uridine-44 in tRNA(Ser) [Homo sapiens] [Reaction:8932765] NSUN6 methylates cytidine-72 in tRNA(Cys) and tRNA(Thr) [Homo sapiens]
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No pathways have been reviewed or authored by tRNA:XPOT:RAN:GTP translocates from the nucleus to the cytosol (6783483)