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Details on Person In transcription-coupled nucleotide excision repair (TC-NER)...
| Class:Id | Summation:6782201 |
|---|---|
| _displayName | In transcription-coupled nucleotide excision repair (TC-NER)... |
| _timestamp | 2015-08-12 14:21:48 |
| created | [InstanceEdit:6782203] Orlic-Milacic, Marija, 2015-06-05 |
| modified | [InstanceEdit:6790548] Orlic-Milacic, Marija, 2015-08-12 |
| text | In transcription-coupled nucleotide excision repair (TC-NER), just like in global genome nucleotide excision repair (GG-NER), the cleavage of the damaged strand of DNA 5' to the site of damage occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The 5' incision is carried out by ERCC1:XPF (ERCC1:ERCC4) complex and precedes the 3' incision by ERCC5 (XPG) (Staresincic et al. 2009). |
| (summation) | [Reaction:6782204] 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER [Homo sapiens] |
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No pathways have been reviewed or authored by In transcription-coupled nucleotide excision repair (TC-NER)... (6782201)
