Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person In the nucleus USP13 binds UFD1 which acts as a scaffold con...

Class:IdSummation:6781895
_displayNameIn the nucleus USP13 binds UFD1 which acts as a scaffold con...
_timestamp2015-06-03 15:49:37
created[InstanceEdit:6781948] Jupe, Steve, 2015-06-03
literatureReference[LiteratureReference:6781915] Ubiquitin-recognition protein Ufd1 couples the endoplasmic reticulum (ER) stress response to cell cycle control
textIn the nucleus USP13 binds UFD1 which acts as a scaffold connecting USP13 to SKP2. USP13 mediates the deubiquitination of SKP2, thereby regulating endoplasmic reticulum-associated degradation (ERAD) by counteracting APC/C(Cdh1)-mediated SKP2 ubiquitination (Chen et al. 2011).
(summation)[Reaction:6781922] USP13 binds UFD1L:SKP2 [Homo sapiens]
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