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Details on Person UniProt:Q9NSI6 BRWD1
| Class:Id | ReferenceGeneProduct:67334 |
|---|---|
| _chainChangeLog | chain:1-2320 added on Sat February 7 2015 |
| _displayName | UniProt:Q9NSI6 BRWD1 |
| _timestamp | 2024-11-03 19:59:54 |
| chain | chain:1-2320 |
| checksum | 109714D79B9057E9 |
| comment | FUNCTION May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.SUBUNIT Interacts with SMARCA4.INTERACTION Ubiquitously expressed (PubMed:12359327). Expressed in respiratory epithelial cells and testis spermatozoa.DISEASE The disease may be caused by variants affecting the gene represented in this entry. |
| description | recommendedName: Bromodomain and WD repeat-containing protein 1 alternativeName: WD repeat-containing protein 9 |
| geneName | BRWD1 C21orf107 WDR9 |
| identifier | Q9NSI6 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Activator Alternative splicing Bromodomain Cell membrane Cell projection Ciliopathy Cilium Cytoplasm Cytoskeleton Flagellum Membrane Nucleus Phosphoprotein Primary ciliary dyskinesia Proteomics identification Reference proteome Repeat Transcription Transcription regulation WD repeat |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9909836] Weiser, Joel, 2024-05-14 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | BRWD1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8865620] ENSEMBL:ENSG00000185658 BRWD1 [Homo sapiens] |
| secondaryIdentifier | BRWD1_HUMAN C9JK25 O43721 Q5R2V0 Q5R2V1 Q6P2D1 Q8TCV3 Q96QG9 Q96QH0 Q9NUK1 |
| sequenceLength | 2320 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:220331] UniProt:Q9NSI6-2 BRWD1 [Homo sapiens] [ReferenceIsoform:220332] UniProt:Q9NSI6-3 BRWD1 [Homo sapiens] [ReferenceIsoform:414769] UniProt:Q9NSI6-1 BRWD1 [Homo sapiens] [ReferenceIsoform:8972307] UniProt:Q9NSI6-4 BRWD1 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:8863306] BRWD1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8960331] BRWD1 [extracellular region] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:Q9NSI6 BRWD1 (67334)
